Trisomy

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Related to trisomy 13: Trisomy 18, Trisomy 8

trisomy

[′trī‚sō·mē]
(cell and molecular biology)
The presence in triplicate of one of the chromosomes of the complement.

Trisomy

 

the presence of one or a few nonhomologous extra chromosomes in the chromosome set of a diploid organism. Organisms (or cells) in which one, two, or more chromosomes present themselves as three homologues are called simple trisomics, double trisomics, and so forth. Trisomy is caused by the failure of chromosomes to separate (nondisjunction) during cell division. Some specific severe disorders are the result of trisomy occurring in specific chromosomes.

References in periodicals archive ?
Dilation and Evacuation Specimens With Abnormal Karyotype and Presence or Absence of Pathologic Findings Cases With Abnormal Karyotype Total Findings, No, (%) Karyotypes with known structural effects Trisomy 21 92 53 (58) Trisomy 18 36 32 (89) Trisomy 13 13 12 (92) Turner syndrome (45,X) 6 4 (67) Trisomy 9, mosaic 2 1 (50) Trisomy 16, mosaic 1 0 (0) Triploid for chromosome 21, 1 1 (100) 18, and 13 Triploid for chromosome 21 and 18 1 1 (100) Triploid for chromosome 21 and 13 1 0 (0) Fragile X syndrome 1 0 (0) 47,XXY 2 0 (0) 48,XXYY 1 1 (100) Karyotypes with uncharacterized structural effects Deletion syndromes (a) 6 3 (50) 45,XY,der(18;21)(q10;10) 1 0 (0) 46,XY,der(8)t(8;8)(p23.
There were two abnormal NIPT results: one was reported as high risk for trisomy 13 and the other as a triploidy (Table 3).
Her understanding is that the test is more than 99% accurate, and she interprets this to mean that the chance of trisomy 13 in her fetus is more than 99%.
Her clinical picture involves the mosaic form of Patau syndrome, also known as trisomy 13, which has caused severe mental retardation and restrains the development of her speech.
Poor families caring for a family member with a rare disease would have no fighting chance, however, since they do not have access to quality and affordable medical care," Cayetano, who lost her youngest child Gabriel from complications of a rare congenital disease called trisomy 13, also known as Patau Syndrome in 2001, said.
The PrenaTest is being further developed "to identify other chromosomal mutations such as Trisomy 13 and 18," said Dr.
Placental abnormalities and preeclampsia in trisomy 13 pregnancies.
Abnormalities of chromosome number occur in aproximatly 32-42% of patients with HPE, most commonly trisomy 13, (2) followed by trisomy 18 and 21.
WORCESTER - A simple blood test done on maternal serum early in the first trimester of pregnancy to determine if a baby has Down syndrome, or Trisomy 13 or Trisomy 18, more severe genetic syndromes, will likely be offered to mothers in Worcester County later this year.
Holoprosencephaly has also been associated with triploidy, trisomy 13, trisomy 18, and a number of other syndromes.