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Trisomy
(redirected from trisomy 21)

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia 0.01 sec.
trisomy [′trī‚sō·mē]
(cell and molecular biology)
The presence in triplicate of one of the chromosomes of the complement.

Trisomy 

the presence of one or a few nonhomologous extra chromosomes in the chromosome set of a diploid organism. Organisms (or cells) in which one, two, or more chromosomes present themselves as three homologues are called simple trisomics, double trisomics, and so forth. Trisomy is caused by the failure of chromosomes to separate (nondisjunction) during cell division. Some specific severe disorders are the result of trisomy occurring in specific chromosomes.



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A literature review also showed that people with Trisomy 21 have a high risk of ocular disorders (Down's Syndrome Medical Interest Group, 2005) and that the prevalence of individuals with a visual acuity of less than 20/40 (0.
That is why this disorder is also referred to as trisomy 21.
Down syndrome, or Trisomy 21, generally is caused by an error in the development of one of the reproductive cells that combine at conception, resulting in an individual with an extra copy of the 21st chromosome.
 
 
 
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