triterpene

(redirected from triterpene acids)
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triterpene

[trī′tər‚pēn]
(organic chemistry)
One of a class of compounds having molecular skeletons containing 30 carbon atoms, and theoretically composed of six isoprene units; numerous and widely distributed in nature, occurring principally in plant resins and sap; an example is ambrein.
References in periodicals archive ?
Active ingredients found in hawthorn include tannins, flavonoids (such as vitexin, rutin, quercetin, and hyperoside), oligomeric proanthocyanidins (OPCs, such as epicatechin, procyanidin, and particularly procyanidin B-2), flavone-C, triterpene acids (such ursolic acid, oleanolic acid, and crataegolic acid), and phenolic acids (such as caffeic acid, chlorogenic acid, and related phenolcarboxylic acids) [40,38].
The most potent were the triterpene acids 4 and 5, reducing 96 and 92% elastase activity, respectively.
Topical anti-inflammatory activity of 2[alpha]-hydroxy pentacyclic triterpene acids from the leaves of Ugni molinae.
Previous work done so far confirmed that these triterpene acids were able to block inflammatory reactions in both acute and chronic inflammation models.
Many of them were triterpene acids which were obtained mainly from F fraction of Z.
Using cyclodextrins it was possible to solubilise mistletoe triterpene acids (mainly oleanolic acid (OA)) and obtain a plant extract with high levels of OA and mistletoe lectins (ML).
In the present study, we determined for the first time the effect of clearly defined mistletoe extracts, containing either lectins (viscum) or triterpene acids (TT) such as oleanolic - and betulinic acid and combinations thereof (viscum IT), against NB.
Regarding the clinical setting a solvent-free application of triterpene acids is required which may be possible by solubilisation of triterpenoids with cyclodextrins (CD).
Conclusions: In recent years controversial data concerning the activity of triterpene acids on proinflammatory mediators have been published.