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tromethamine

   Also found in: Medical, Wikipedia 0.03 sec.
tromethamine [trō′meth·ə‚mēn]
(organic chemistry)
C4H11NO3A crystalline compound with a melting point of 171-172°C; soluble in water, ethylene glycol, methanol, and ethanol; used to make surface-active agents, vulcanization accelerators, and pharmaceuticals, and as a titrimetric standard. Also known as THAM; trimethylol aminomethane; TRIS; trisamine; tris buffers.


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Examples of these group of drugs include sodium cromoglycate and lodoxamide tromethamine.
DDMAC determined that a professional journal advertisement for Acular LS (ketorolac tromethamine ophthalmic solution) was false or misleading because it broadened the indication, presented unsubstantiated claims and omitted important risk information.
Akorn also announces the launch of the generic version of Acular[R] (Ketorolac Tromethamine Ophthalmic), a drug with estimated brand sales of $119 million in 2008 according to IMS data.
 
 
 
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