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tumor suppressor gene

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia 0.03 sec.
tumor suppressor gene [¦tüm·ər sə′pres·ər jēn]
(cell and molecular biology)
A class of genes which, when mutated, predispose an individual to cancer by causing the loss of function of the particular tumor suppressor protein encoded by the gene.


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Nairn has identified a Xiphophorus gene correlating to the p16 tumor suppressor gene in humans that seems to be associated with susceptibility to developing melanoma upon exposure to UV light.
The goal of cancer treatment with CDK inhibitors is to emulate tumor suppressor gene behavior and cause cancer cells to die.
The development of aneuploidy, researchers suspect, advances tumor formation by eliminating tumor suppressor genes or by increasing the number of growth-promoting genes.
 
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