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tumor suppressor gene

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia 0.01 sec.
tumor suppressor gene [¦tüm·ər sə′pres·ər jēn]
(cell and molecular biology)
A class of genes which, when mutated, predispose an individual to cancer by causing the loss of function of the particular tumor suppressor protein encoded by the gene.


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All of these new pathways are important candidates for novel tumor suppressor genes and could be involved in cancer progression.
9781604563269 Tumor suppressor genes in breast cancer.
Previous studies have shown that miR-21 interrnpts the activity of two tumor suppressor genes, PTEN (for phosphatase and tensin homolog) and TPM1 (tropomyosin 1).
 
 
 
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