tumorigenic

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tumorigenic

[¦tü·mə·rə′jen·ik]
(medicine)
Tumor-forming.
References in periodicals archive ?
Inhibition of the long non-coding RNA MALAT1 suppresses tumorigenicity and induces apoptosis in the human ovarian cancer SKOV3 cell line.
microRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells.
Following parameters have been evaluated during optimization: toxicity risk (mutagenicity, tumorigenicity, irritant effect and reproductive effect), physico-chemical properties (clogP, logS, TPSA and molecular weight), and drug prediction (drug likeness and drug score) [8].
sup][4] Another study reported that CDCA7L overexpression raises the progression of hepatocellular carcinoma cell cycle from G0/G1 phase into S phase while CDCA7L knockdown overturns tumorigenicity and decreases tumor size in vivo .
Neural Stem Cell Tumorigenicity and Biodistribution Assessment for Phase 1 Clinical Trial in Parkinson's Disease," Scientific Reports 6, 30 September 2016, 34478 (2016), DOI:10.
G-protein-coupled receptor genes as protooncogenes: Constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity.
miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation.
WAF] a CDKs inhibitor, third the dramatic degradation of RB, which is involved in transcriptional regulation of genes involved in cell cycle control and of differentiation-related genes, and fourth the downregulation of SOX2, which is a regulator of GBM tumorigenicity.
Imatinib mesylate inhibits platelet-derived growth factor receptor phosphorylation of melanoma cells but does not affect tumorigenicity in vivo.
Hepatitis B virus X (HBx) induces tumorigenicity of hepatic progenitor cells in 3,5-diethoxycarbonyl-1,4-dihydrocollidine-treated HBx transgenic mice," Hepatology, vol.
Hsiao, "Suppression of the tumorigenicity of mutant p53-transformed rat embryo fibroblasts through expression of a newly cloned rat nonmuscle myosin heavy chain-B," Oncogene, vol.
Supporting this finding, it has been found that inhibition of CYP2E1 and DMN-dI activity played a significant role in decreasing the tumorigenicity and the carcinogenicity caused by N-nitrosamines [23, 28, 29].