Common cytochemical and ultrastructural characteristics of cells producing polypeptide hormones (the APUD series) and their relevance to thyroid and ultimobranchial
C cells and calcitonin.
C cells are neural crest-derived cells arising from ultimobranchial
TZ indicates the point of fusion of ultimobranchial
body and principal median thyroid process.
Effects of the insecticide cypermethrin on plasma calcium and ultimobranchial
gland of a teleost Heteropneustes fossilis.
Effects of calcitonin administration on the ultimobranchial
body and parathyroid glands of the freshwater snake, Natrix piscator.
gland and congenital thyroid abnormalities in man.
1-4) Each arch is composed of ectoderm, which will form the epidermis and sensory neurons; the neural crest, from which will develop the skeletal and connective tissues; the mesoderm, from which will arise the musculature and endothelial cells; and the endoderm, which will form the epithelial lining of the pharynx, the taste buds, the thyroids, parathyroids, ultimobranchial
glands, and thymus?
The second group consists of carcinoma arising from parafollicular cells of ultimobranchial
body of neural crest, which is the medullary carcinoma.
C cells originate in the neural crest and reach their usual anatomic location as parafollicular cells in the thyroid via the ultimobranchial
bodies that migrate to fuse with the lateral lobes of thyroid.