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Uridine

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uridine [′yu̇r·ə‚dīn]
(biochemistry)
C9H12N2O6A crystalline nucleoside composed of one molecule of uracil and one molecule ofD-ribose; a component of ribonucleic acid.
Uridine 

(also D-ribosyl uracil), an organic substance and nucleoside composed of residues of the pyrimidine uracil and the carbohydrate ribose. Uridine occurs either as a white powder or as long acicular or prismatic crystals. It is soluble in water, acids, and alkalies but insoluble in ether and concentrated ethanol; its molecular weight is 244.2. Uridine is present in all living cells as a constituent of ribonucleic acids. It plays an important role in carbohydrate metabolism, forming part of many coenzymes.
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Three active principles are interlocked: ethyl ferulate, a natural antioxidant with UV absorbing properties, neutralizes dangerous oxygen radicals and reduces the dose of UV radiation that penetrates the skin; carnosolic acid combats free radicals--one of the main causes of DNA damage and uridine monophosphate (UMP), a biochemi-cal pre-cursor to the synthesis of nucleotides, supports the repair of DNA in the cell.
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Repligen Corporation (Waltham, MA) announced that it has exclusively licensed worldwide rights for the use of uridine in the treatment of patients with bipolar disorder from McLean Hospital.
Repligen Licenses Patent Rights for Treatment of Bipolar Disorder by BIOTECH Patent News
UGT encodes the drug's main metabolizing enzyme in the body, uridine diphosphate-glucuronosyl transferase.
Screening for gene mutation helps predict pediatric kidney transplant ... by Transplant News
 
 
 
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