Distinctions in vaginal bacterial communities between women with and without BV were evident by 1989, and the term bacterial vaginosis
appears in the literature.
18 that the FDA had granted approval to secnidazole (Solosec) 2 g oral granules for the treatment of bacterial vaginosis
in adult women.
To study the prevalence of bacterial vaginosis
in pregnancy after 20 weeks of gestation.
The product's approval in the US was supported by various studies including two key trials in bacterial vaginosis
along with an open label safety study that proved efficacy for single-dose of the drug in two gram strength.
Cuando proliferan las bacterias que habitan en la vagina y disminuyen los lactobacilos, ocurre un desequilibrio en su flora, alterandose el grado de acidez, favoreciendo aun mas el desarrollo de la microbiota genital, lo que lleva a la aparicion de enfermedades como la vaginitis y la vaginosis
, entre otras (1).
is the most prevalent gynecological infection in the US among women ages 15 to 44.
, gonorrhea, trichomoniasis, vaginal discharge, vulvovaginal candidiasis.
vaginalis, Gram stain matching with bacterial vaginosis
(%), clinical diagnosis (%), and pregnancy (%) are presented in Table 1.
bacteriana (VB) se define como una alteracion de la flora vaginal (1), en la cual hay disminucion de los lactobacilos y aumento de bacterias anaerobias y de otros microorganismos como la Gardnerella vaginalis, el Mobiluncus sp.
It also reviews key players involved in the therapeutic development for Bacterial Vaginosis
and special features on late-stage and discontinued projects.
and lactobacillosis, two recently identified disorders characterized by Lactobacillus overgrowth, are often mistaken for vulvovaginal candidiasis.
(BV) is a condition in which the normal balance of bacteria in the vagina is disrupted and replaced by an overgrowth of certain bacteria.