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valine |
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valine (văl`ēn), organic compound, one of the 22 α-amino acids amino acid (əmē`nō) ..... Click the link for more information. commonly found in animal proteins. Only the l-stereoisomer appears in mammalian protein. It is one of several essential amino acids needed in the diet, as the human body cannot synthesize it from simpler metabolites. Young adults need about 23 mg of this amino acid per day per kilogram (10 mg per lb) of body weight. Valine can be degraded into simpler compounds by the enzymes of the body; an inherited defect in one of the enzymes involved in this process results in a rare disorder called maple syrup urine disease. Valine contributes to the structure of proteins into which it has been incorporated by the tendency of its side chain to participate in hydrophobic interactions. The structure of valine was established in 1906, after it had been first isolated from albumin in 1879. See isoleucine isoleucine (ī'səl ..... Click the link for more information. . valineOne of the essential amino acids, found in most proteins. Produced industrially by hydrolysis of proteins or by chemical synthesis, it is used in biochemical and nutritional research and as a dietary supplement. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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In another study, a strain of typical BSE injected into humanized mice encoding valine at codon 129 showed a glycopattern indistinguishable from the same subtype of sporadic CJD (15). I have also supplemented with the essential amino acids--methionine, phenylalanine, tryptophan, leucine, isoleucine, valine, lysine, and threonine--but only after the previously listed supplements have been given. N-Methylcarbamoyl adducts at the N-terminal valine of globin in workers exposed to N,N-dimethylformamide. |
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