valine


Also found in: Dictionary, Thesaurus, Medical, Financial, Acronyms, Wikipedia.
Related to valine: isoleucine, histidine, serine

valine

(văl`ēn), organic compound, one of the 22 α-amino acidsamino acid
, any one of a class of simple organic compounds containing carbon, hydrogen, oxygen, nitrogen, and in certain cases sulfur. These compounds are the building blocks of proteins.
..... Click the link for more information.
 commonly found in animal proteins. Only the l-stereoisomer appears in mammalian protein. It is one of several essential amino acids needed in the diet, as the human body cannot synthesize it from simpler metabolites. Young adults need about 23 mg of this amino acid per day per kilogram (10 mg per lb) of body weight. Valine can be degraded into simpler compounds by the enzymes of the body; an inherited defect in one of the enzymes involved in this process results in a rare disorder called maple syrup urine disease. Valine contributes to the structure of proteins into which it has been incorporated by the tendency of its side chain to participate in hydrophobic interactions. The structure of valine was established in 1906, after it had been first isolated from albumin in 1879. See isoleucineisoleucine
, organic compound, one of the 20 amino acids commonly found in animal proteins. Only the l-stereoisomer appears in mammalian protein.
..... Click the link for more information.
.

Valine

 

α-aminoisovaleric acid, (CH3)2,CHCH(NH2)— COOH, one of the irreplaceable amino acids. Valine is included in proteins in the form of the L-isomer. The amount of valine in protein usually varies from 4.1 percent (horse myoglobin) to 7-8 percent (human serum albumen, milk casein) and sometimes 13-14 percent (connective-tissue elastin). The absence of valine from food makes it protein-deficient and results in a negative nitrogen balance.

valine

[′va‚lēn]
(biochemistry)
C5H11NO2 An amino acid considered essential for normal growth of animals, and biosynthesized from pyruvic acid.
References in periodicals archive ?
The optimal ratio of isoleucine to lysine may affect the broilers' metabolic efficiency and growth performance coupled to the utilization of valine and other limiting amino acids (Corzo et al.
The selected bacterial isolates which produced cysteine, methionine, glutamic acid and valine in significant amounts were further proceeded with different fermentation media containing all the essential ingredients required for amino acids biosynthesis (Ali et al.
The mushrooms were poor in valine, threonine, leucine and methionine (or cysteine).
However, the values for lysine in Irvigna gabonesis, isoleucine, valine and phenylalanine in Irvigna gabonesis and Citrullus colocynthis, were lower than the values in an egg.
The cutaneous sample of these peoples were cultured in mycobiotic agar while the fungus strain by macroscopic and microscopic studies were designated as only on peoples serum that suffers from dermatophytosis due to trichophyton mentagrophytes agent to determination of valine amino acid, HPLC experiment were exert.
In the Journal of Nutrition, an international team of researchers report an association between an increased intake of the branched-chain amino acids (BCAAs) leucine, isoleucine, and valine and a reduced risk of being overweight or obese.
Last year, scientists showed that the same amino acids, leucine, isoleucine and valine, could extend the lifespan of single-celled yeast.
Last year scientists showed that the same amino acids, leucine, isoleucine and valine, could extend the lifespan of single-celled yeast.
Leucine, isoleucine and valine - known as branched-chain amino acids - account for a fraction of the 20 amino acids from which proteins are made, but appear to have special anti-ageing properties.
Last year, scientists showed the same acids - leucine, isoleucine and valine, known as BCAAs - extended the lifespan of yeast.
Our recent study shows that if you make a single amino acid change from valine to methionine at position 66 it leads to a decrease in the amount of BDNF that gets secreted.