valine


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Related to valine: isoleucine, histidine, serine

valine

(văl`ēn), organic compound, one of the 22 α-amino acidsamino acid
, any one of a class of simple organic compounds containing carbon, hydrogen, oxygen, nitrogen, and in certain cases sulfur. These compounds are the building blocks of proteins.
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 commonly found in animal proteins. Only the l-stereoisomer appears in mammalian protein. It is one of several essential amino acids needed in the diet, as the human body cannot synthesize it from simpler metabolites. Young adults need about 23 mg of this amino acid per day per kilogram (10 mg per lb) of body weight. Valine can be degraded into simpler compounds by the enzymes of the body; an inherited defect in one of the enzymes involved in this process results in a rare disorder called maple syrup urine disease. Valine contributes to the structure of proteins into which it has been incorporated by the tendency of its side chain to participate in hydrophobic interactions. The structure of valine was established in 1906, after it had been first isolated from albumin in 1879. See isoleucineisoleucine
, organic compound, one of the 20 amino acids commonly found in animal proteins. Only the l-stereoisomer appears in mammalian protein.
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Valine

 

α-aminoisovaleric acid, (CH3)2,CHCH(NH2)— COOH, one of the irreplaceable amino acids. Valine is included in proteins in the form of the L-isomer. The amount of valine in protein usually varies from 4.1 percent (horse myoglobin) to 7-8 percent (human serum albumen, milk casein) and sometimes 13-14 percent (connective-tissue elastin). The absence of valine from food makes it protein-deficient and results in a negative nitrogen balance.

valine

[′va‚lēn]
(biochemistry)
C5H11NO2 An amino acid considered essential for normal growth of animals, and biosynthesized from pyruvic acid.
References in periodicals archive ?
Regarding the significance of increased plasma branched-chain amino acid concentrations for the diagnosis of MSUD, leucine, valine, and isoleucine should exceed ~400, 600, and 250 [micro]mol/L, respectively, to allow reliable differentiation of MSUD-induced increases from secondary disturbances of branched-chain amino acid metabolism that occur, e.
Second, he sees a "strong possibility" that the valine form will find use in adult respiratory distress syndrome, a disease that resembles a very rapidly developing emphysema.
Valine satisfies all of the independent director criteria of the Nasdaq National Market.
Norm Valine adds, "I am proud to offer the latest technology to everyone, right in their backyard.
Une grande partie se tient de pres car a l'exception de Valine de Nganda et Quokin d'Arline, qui restent sur de mauvais essais, les autres concurrents possedent chacun a sa facon des arguments pour venir demeler l'echeveau de ce quarte quinte, bien compose il faut le reconnaitre.
Gnarly's BCAA formula includes Leucine, Isoleucine, and Valine - the three most important amino acids for protein synthesis and the building of muscle.
Vital for muscle protein synthesis, BCAA provides the clinically proven ratio of branched chain amino acids -- leucine, isoleucine and valine -- essential nutrients that the body cannot produce and must be acquired through diet or supplementation.
Threonine, valine, methionine, leucine, cysteine, arginine and tyrosine contents were either low or absent.
The effects of GanedenBC30 with protein were examined in a randomized, double-blind crossover clinical trial on key amino acids, including leucine (the regulator for muscle protein synthesis), isoleucine and valine (branched chain amino acids), as well as histidine, alanine, asparagines, citrulline, cystine, glutamine (a key amino acid for supporting ph balance and the immune system), methionine, ornthinine, serine, threonine, tryptophan and phenylalanine.
The visit has been followed by a lunch offered by Jean and Valine Makhlouf (exclusive agents of an important Italian clothes brand).
The findings confirmed that among people with a psychiatric diagnosis, those with the methionine ("met") variation of the gene had a higher risk of suicidal behaviour compared to those with the valine variation.
These include: arginine, isoleucine, leucine, lysine, histidine, methionine, phenylalanine, threonine, tryptophan, and valine (Igwenyi, 2008).