8) Coamplification of the FMS-like tyrosine kinase 4 (FLT4) gene encoding the vascular endothelial growth factor receptor 3 (VEGFR3), in association with MYC amplification, was found by Guo et al (10) in 25% of secondary angiosarcomas but not in other radiation-associated, atypical vascular lesions
Endovascular papillary angioendothelioma of childhood: A vascular lesion
possibly characterized by "high" endothelial cell differentiation.
The histologic spectrum ranges from well-differentiated tumors that mimic benign vascular lesions
to poorly differentiated tumors that present as undifferentiated malignant neoplasms.
Confusion may stem from the fact that two types of classifications are employed: clinically useful classifications for patient management and the more inclusive pathologic classifications, which specify the six categories of vascular lesions
Ki-67 index can be used as a diagnostic tool to distinguish between benign and malignant vascular lesions
of the breast.
Proliferative vascular lesions
are classified along a spectrum that ranges from reactive to neoplastic.
Because of its histologic similarity to other vascular lesions
, the differential diagnosis may include cavernous and capillary hemangioma, (8) bacillary angiomatosis, (9) and other rare vascular lesions
< 6 MONTHS > 6 MONTHS 1-5 YEARS -1 YEAR Vascular tumours 7 17 6 Vascular malformations 1 0 4 8 (18%) 17 (39%) 10 (23%) VASCULAR LESION
> 5 YEARS Vascular tumours 9 39(89%) Vascular malformations 0 5 (11%) 9 (20%) 44 (100%) Table 2: Sex Distribution VASCULAR LESION
MALES FEMALES Vascular tumours 11 28 Vascular malformations 3 2 Total 14 (32%) 30 (68%) Table 3: Distribution of Lesions at different locations.
Despite its benign nature, the vascular lesion
and associated IPEH extended to the sphenoid sinus and sella with bony destruction.
The vascular lesion
in the mandible was extracted transorally, and the bony defect was closed with Medpore porous polyethylene (figure 4).
Funnel Catheter provides temporary occlusion proximal to a vascular lesion
with an innovative funnel that allows the physician to perform Focused Aspiration[TM], directing maximum aspirative force and dramatically enhancing the efficiency of removal of thrombus or emboli.
The patient underwent resection of the middle ear vascular lesion
via the postauricular approach.