vinblastine


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.
Related to vinblastine: vincristine

vinblastine

[vin′bla‚stēn]
(pharmacology)
C46H58O9N4 An alkaloid obtained from the periwinkle plant (Vinca rosea) and used, as the sulfate salt, as an antineoplastic drug.
References in periodicals archive ?
Doxorubicin (DOX), vinblastine (VBL), verapamil (VPL) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) were purchased from Sigma (Saint Quentin Fallavier, France).
0% and vinblastine [greater than or equal to] 96% from Sigma-Aldrich (Munich, Germany) were provided by the Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry of the Johannes Gutenberg University (Mainz, Germany) and dissolved in PBS (Invitrogen, Eggenstein, Germany) at a concentration of 10 mM.
Treatment of reticuloendotheliosis with vinblastine sulfate.
While there is a small chance that vinblastine may kill the tumour on Megan's brain the drug is normally intended simply to block any further growth.
Thus, the present study aimed to evaluate the MDR-modulatory activity of the quercetin-POM conjugates 2 and 3 on the antitumor activity of the anticancer agents doxorubicin, actinomycin D, vinblastine, and paditaxel against MDR cancer cell lines.
After the patient received 4 cycles of MVAC chemotherapy (methotrexate, vinblastine, adriamycin, and cisplatin), radiological findings demonstrated that MVAC therapy was not effective.
ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) chemotherapy produces a high cure rate in patients with Hodgkin lymphoma (HL).
In 2005 she began a course of Vinblastine chemotherapy which the family were told had only a 10% chance of curing the cancer, and which was expected to last six to 12 months.
The patient was treated with dexamethasone, doxorubicin, cyclophosphamide, and vinblastine.
The results led some at the meeting to conclude that standard care should now include the MVAC regimen, which is three cycles of methotrexate, vinblastine, doxorubicin, and cisplatin.
The bladder cancer therapeutics market was dominated by generics such as vinblastine, cisplatin and methotrexate, as well as Bacillus Calmette-Gurin (BCG) and mitomycin C.