vincristine


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Related to vincristine: cyclophosphamide, methotrexate, prednisone

vincristine

[vin′kri‚stēn]
(pharmacology)
C46H56O10N4 An alkaloid extracted from the periwinkle plant (Vinca rosea) and used, as the sulfate salt, as an antineoplastic drug. Also known as leurocristine.
References in periodicals archive ?
6) The severity of vincristine neurotoxicity increases with higher dosage, patient hypersensitivity to vincristine, pre-existing liver dysfunction, and concomitant use of other metabolism-inhibiting drugs such as allopurinol, erythromycin, isoniazid, phenytoin, or itraconazole.
10) There are some other case reports where authors have used Vincristine to treat KMS.
In current study based on done observations, the damages resulted from vincristine on treatment group neonates expressed as hyperemia and oedema in pia matter.
cells (Panel 1) and H1299 cells (Panel 2) with usnic acid (1b and 2b), taxol (1c and 2c) and vincristine (1d and 2d).
badrakema, was investigated on improvement of vincristine cytotoxicity in TCC cells.
A therapeutic monoclonal antibody approved as first-line treatment for diffuse large B-cell, CD20-positive, non-Hodgkin's lymphoma (NHL), taken in combination with CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) or with other anthracycline-based chemotherapy regimens.
The regimen, known as the Stanford V, involves a combination of doxorubicin, vinblastine, nitrogen mustard, vincristine, bleomycin, etoposide, and prednisone with differing levels of radiation given for 8 or 12 weeks.
The committee will also review Ilex/Enzon's liposomal vincristine formulation Marqibo NDA (21-600) for relapsed aggressive non-Hodgkin's lymphoma and Ilex' Clolar (clofarabine) NDA (21-673) for pediatric patients (1-21 years) with refractory or relapsed acute leukemias on Dec 1.
Cancer-fighting weed derivatives include vinblastine for Hodgkin's disease and vincristine for childhood leukemia, reports John Richard Stepp, a University of Florida anthropologist, in the Journal of Ethno-Pharmocology.
The drug Vincristine should have been administered intravenously.
She was then started on vincristine and a gastrostomy tube was placed; later, total parenteral nutrition was given.