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vincristine |
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vincristine [vin′kri‚stēn] (pharmacology) C46H56O10N4An alkaloid extracted from the periwinkle plant (Vinca rosea) and used, as the sulfate salt, as an antineoplastic drug. Also known as leurocristine. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The treatment of choice is chemotherapy, which usually includes cyclophosphamide, vincristine, and prednisone. The patient was previously treated with vincristine and prednisone, followed by chemotherapy according to the R-CHOEP-14 protocol (3 cycles) (November 2003 through January 2004). Although a relationship between the gross motor problems and vincristine neurotoxicity seemed plausible, that explanation has not been supported statistically. |
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