vincristine


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Related to vincristine: cyclophosphamide, methotrexate, prednisone

vincristine

[vin′kri‚stēn]
(pharmacology)
C46H56O10N4 An alkaloid extracted from the periwinkle plant (Vinca rosea) and used, as the sulfate salt, as an antineoplastic drug. Also known as leurocristine.
References in periodicals archive ?
Optic vesicle defects induced by vincristine sulfate: An in vivo and in vitro study in the mouse embryo, Teratology, 29(2): 223-239.
In order to check the effect of mogoltacin on cytotoxicity of vincristine, it was necessary to find IC50 of vincristine on TCC cells first.
The objective of this study was to evaluate the effectiveness of Anisina either alone or in combination with vincristine, in a mouse model of human neuroblastoma (CHLA20).
An Open-Label, Randomized Study of Bendamustine and Rituximab (BR) Compared with Rituximab, Cyclophosphamide, Vincristine, and Prednisone (R-CVP) or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in First-Line Treatment of Patients with Advanced Indolent Non-Hodgkin's Lymphoma (NHL) or Mantle Cell Lymphoma (MCL): The Bright Study
The pain subsided without acute surgical intervention and mixed-type neuropathy-particularly drug-related-was considered and therefore vincristine (Vincristine Amphar Flacon 1 mg; Atabay) treatment was not continued.
Marqibo is a novel, targeted, Optisome(TM) encapsulated formulation of vincristine sulfate, a widely-used chemotherapy, which has shown promising anti-cancer activity in patients with ALL, non-Hodgkin's lymphoma, Hodgkin's disease, and melanoma in several clinical trials.
Patients received two cycles of ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine), MOPP/ABV (mechlorethamine, vincristine, procarbazine, and prednisone), or other ABVD-like chemotherapy.
In the second part of the study we investigated Viscum album/Qu (VA/Qu) extract (2000 ng lectin + 6 [micro]g viscotoxin/ml) and Vincristine on proliferation and IL-6 related parameters.
The treatment of choice is chemotherapy, which usually includes cyclophosphamide, vincristine, and prednisone.
In a randomized multicenter trial headed by the Eastern Cooperative Oncology Group, 632 patients were treated with CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) chemotherapy, with or without rituximab induction, said Dr.
In February 1998, another relapse was diagnosed and the patient was given chemotherapy, according to protocol COPP (cyclophosphamide, vincristine, prednisolone, procarbazine) four times.