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visceral leishmaniasis |
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visceral leishmaniasis [′vis·ə·rəl ‚lēsh·mə′nī·ə·səs] (medicine) A severe, generalized, and often fatal infection, caused by any of three pathogenic hemoflagellates of the genusLeishmania, affecting organs rich in endothelial cells; accompanied by fever, spleen and liver enlargement, anemia, leukopenia, skin pigmentation, and changes in plasma protein. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Visceral leishmaniasis or kala-azar, the often fatal form of the disease, is caused by species of the Leishmania donovani complex. DNDi's initial drug development efforts are aimed at chloroquine-resistant malaria, human African trypanosomiasis (sleeping sickness), visceral leishmaniasis (also called kala-azar), and Chagas disease. Visceral leishmaniasis is usually curable if caught early, but treatment involves a month or two of daily injections, an expensive regimen for people in developing countries and one that sometimes causes significant side effects. |
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