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warfarin |
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warfarin (wôr`fərĭn), anticoagulant anticoagulant (ăn'tēkōăg`yələnt) ..... Click the link for more information. used to treat blood clots. In large doses it causes bleeding. Warfarin, mixed with bait, is used in rodent control. warfarinAnticoagulant drug, marketed as Coumadin. Originally developed to treat thromboembolism (see thrombosis), it interferes with the liver's metabolism of vitamin K, leading to production of defective coagulation factors. Warfarin therapy risks uncontrollable hemorrhage, either spontaneously or from any cut or bruise; it requires frequent checks to maintain the proper level in the blood. In high concentrations, warfarin is used as a rodent poison, causing death by internal bleeding. |
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About 200,000 Australians undergo Warfarin therapy, necessitating regular monitoring of dotting times. Balancing clot prevention and bleeding risk is a particularly delicate act with warfarin. The most common problems were confusion, oversedation, hallucinations, or bleeding, and the drugs causing the most problems were warfarin and antipsychotics; 73% of the most severe injuries were preventable, according to the research. |
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warfarin
