In order to understand whether a diet rich in healthy compounds might favorably influence platelet and white blood cell
levels, investigators conducted an analysis of the eating habits of nearly 15,000 healthy Italian men and women ages 35 or older as part of the large epidemiological "Moli-sani" study, named for the inhabitants of the Molise region of Central and Southern Italy.
The report, published in the British Journal of Sports Medicine, found higher white blood cell
counts were found in men with a greater proportion of body fat.
rhG-CSF functions within the body to stimulate production of more white blood cells
, helping to reverse neutropenia so that cancer patients undergoing chemotherapy can continue with as near to normal white blood cell
counts as possible.
Through continual adaptation, a dizzying number of our white blood cells
learn to recognize a specific bacterium, virus, fungus, or even a normal cell that has become cancerous, by responding to unique proteins on the cell surfaces.
Marrow-stimulating factors, such as NEUPOGEN(R) (Filgrastim), stimulate the production of infection-fighting white blood cells
Gombart of the University of California, Los Angeles (UCLA) and his colleagues reported that vitamin D boosts production in white blood cells
of one of the antimicrobial compounds that defends the body against germs.
As a result of reciprocal translocation, a new and abnormal protein, Bcr-Abl, causes the uncontrolled proliferation of white blood cells
The disease can then advance to the accelerated stage, during which white blood cell
counts increase even more.
Jamas noted that the studies related to production of precursors of white blood cell
and platelet populations build on previous data and are an important step toward clinical trials with Betafectin in chemotherapy patients.
White blood cells
that react against myelin, specifically against a major component called myelin basic protein, were discovered in the animal form of MS, called EAE (experimental autoimmune encephalomyelitis) and in human MS.
Its product line includes LEUKINE(R) (Sargramostim), a white blood cell
stimulant, and chemotherapeutics such as NOVANTRONE(R) (mitoxantrone HCl) and Leucovorin Calcium.
The decreased white blood cell
production weakens the immune system and decreased red blood cell production leads to fatigue and weakness, while the myeloma tumors cause bone destruction, pain and fractures.