wild type

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wild type

[′wīld ‚tīp]
(genetics)
The most prevalent allele or character in the wild organism.
References in periodicals archive ?
The effect of Date palm pollen grain extract on pollen tube morphology is present in the table 3, table 4 shows Chi-Square Test to determine significant difference between phenotypic groups of pollen tubes and treatments, percentage of wildtype in the treatments is displayed in figure 1, images for five phenotype groups, balloon tip, swollen, thin, wavy, and wildtype are displayed in Figures 2-6.
Using these populations, subsets were created on the basis of the therascreen KRAS test result: "KRAS evaluated," consisting of all patients who had KRAS status available; "KRAS wild type," consisting of "KRAS evaluated" who had KRAS wildtype tumors; "KRAS mutant," consisting of "KRAS evaluated" who had KRAS mutant tumors; and "KRAS not evaluated," consisting of all patients who had no KRAS status available.
The researchers found that flies which had a copy of the human CASK gene could remember like a normal wildtype fly.
A previous mutagenesis project discovered that uvrD mutants of Pst DC3000 are less virulent than the wildtype strain.
These studies have shown that the administration of cTnI-specific monoclonal antibodies (MAbs) induces autoimmune dilated cardiomyopathy in wildtype mice (11) and that provocation of an autoimmune response to cTnI, but not cTnT, leads to increased myocardial inflammation and cardiac dysfunction (12, 13).
Results: Quantification of proliferating cells showed that the VEGF 120 mice have significantly reduced numbers of PHH3-positive cells compared to wildtype (Figure 1A; p=0.
Wildtype p53 in normal cells primarily exists in an inactive form that can be degraded rapidly by proteolysis and is maintained at relatively low levels.
However, anti-EGFR therapy is only effective in tumours that are KRAS and BRAF wildtype.
albicans PLD1 is involved in hyphal development in vitro and PLD1 deficient yeast are avirulent compared to wildtype in mouse models of candidiasis.
Merck Serono, a division of Merck KGaA, Darmstadt, Germany, announced today that ErbituxA (cetuximab) can now be used in Japan in combination with chemotherapy in the 1st-line treatment for patients with epidermal growth factor receptor (EGFR)-expressing, curatively unresectable (inoperable), advanced or recurrent colorectal cancer (mCRC) carrying the KRAS wildtype gene.
Therefore, this situation would be more common in a Caucasian or black population than in an Asian population because of the frequency of the wildtype RHD in the respective populations.
In the setting of a hereditary syndrome, germline mutations of EXTI and EXT2 are present, with accompanying loss of the wildtype allele in the cartilage cap of the osteochondroma.