xenobiotic


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xenobiotic

[‚zēn·ə·bī′äd·ik]
(biochemistry)
A chemical that is not normally found in the body, such as a drug.
References in periodicals archive ?
Molecular modeling studies of CdGSTP1-1 showed similar overall fold and domain organization, however major variations were identified in C-terminal helix that may affect xenobiotic substrate recognition and catalytic mechanism.
It is not metabolized; but if it comes across a toxic metal for which it has greater affinity, EDTA drops the magnesium, surrounds the xenobiotic metal, and transports it safely through the kidneys.
CY3A4 is the most important drug or xenobiotic metabolising enzyme that plays a key role in the biotransformation of foreign compounds, which are introduced into the body for specific reasons [1].
Identifying and removing xenobiotic substances and exposures that may challenge iron binding, transport, and utilization.
Nuclear pregnane X receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.
Xenobiotic metabolism gene expression in the Epiderm in vitro human epidermis model compared to human skin.
Pharmacokinetics, poisoning, substance abuse, and breast-feeding toxicokinetics are explained relevant to how xenobiotics may behave differently in these conditions.
Most recently Heidi was with XenoBiotic Laboratories, a subsidiary of WuXi AppTec, Inc.
The xenobiotic metabolism study is fundamental to a rational understanding of the pharmacology, toxicology research on cancer and addiction.
Being exposed to xenobiotic (drug) stress, an organism is challenged to rapid and appropriate adaptation by activating constitutive and expressing inducible systems, thus attenuating negative biological consequences.
These strategies would use different groups of microorganisms and plants to detoxify toxic xenobiotic compounds, such as synthetic organochlorides, crude oil and more.