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C21H30O3 A steroid hormone secreted in small amounts by the adrenal cortex.



(also cortexone), an intermediate product in the biosynthesis of hormones of the adrenal cortex. Formed primarily from progesterone, it is a mineralocorticoid, that is, an active regulator of mineral metabolism, and in this connection the most stable preparation of deoxycorticosterone is deoxycorticosterone acetate, which is used in medicine.

References in periodicals archive ?
Corticosterone, 11-deoxycorticosterone, and aldosterone concentrations in the medium were measured with HPLC using UV detection (241 nm).
We have tentatively identified 11-deoxycorticosterone, androstadienedione, and androstenedione in the effluent.
Simultaneous radioimmunoassay of plasma aldosterone, corticosterone, 11-deoxycorticosterone, progesterone, 17-hydroxyprogesterone, 11-deoxycortisol, cortisol and cortisone.
Deficiency in the CYP21 gene prevents the conversion of 17-hydroxyprogesterone to 11-deoxycorticosterone, leading to an excessive production of androgen, which in turn affects several stages of growth and development (1).