2,4,5-trichlorophenoxyacetic acid


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2,4,5-trichlorophenoxyacetic acid

[¦tü ¦fȯr ¦fīv trī¦klȯr·ō·fə¦näk·sē·ə¦sēd·ik ′as·əd]
(organic chemistry)
C6H2Cl3OCH2CO2H A toxic, light-tan solid; soluble in alcohol, insoluble in water; melts at 152°C; used as a defoliant, plant hormone, and herbicide. Also known as 2,4,5-T.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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Topics considered here include the need for high purity [e.g., hexachlorocyclohexane and polychloroborane isomers and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T)], environmental degradation and the bioactivity of resulting photoproducts and metabolites, pesticide photochemistry (including the use of structural optimization, photostabilizers, and photosensitizers to achieve suitable persistence), the presence of multiple active ingredients in botanical insecticides, the need to consider compounds with common mechanisms of action, issues related to primary and secondary targets, and chemically induced or genetically modified changes in plant biochemistry.
The greening of pesticide-environment interactions: some personal observations
Teratology studies with 2,4,5-trichlorophenoxyacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Retinoic acid drives aryl hydrocarbon receptor expression and Is instrumental to dioxin-induced toxicity during palate development
The phenoxyacetic acids 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) constituted Hormoslyr (Gullvik, Sweden), one of the most widely used pesticides in Sweden during that period.
Is the decline of the increasing incidence of non-Hodgkin lymphoma in Sweden and other countries a result of cancer preventive measures?

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