two-dimensional gel electrophoresis

(redirected from 2-D electrophoresis)

two-dimensional gel electrophoresis

[¦tü·də‚men·shən·əl ¦jel i‚lek·trō·fə′rē·səs]
(cell and molecular biology)
A type of gel electrophoresis in which proteins are first separated by charge and then by molecular weight, enabling the analysis of complex protein mixtures.
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Interchangeable modular inserts enable users to combine vertical PAGE with capillary gel IEF to perform 2-D electrophoresis followed by Western transfer for enhanced sensitivity.
Products such as TotalLab and modas offer analysis and data mining tools for 1-D and 2-D electrophoresis gels and microarrays - the essence of genomics and proteomics.
"I think that's where Bio-Rad can really make a difference because we're already strong in chromatography and sample preparation, and we're the market leader, for example, in 2-D electrophoresis," Dr.
Also, the joint research group has successfully reduced in size the new system to a quarter the conventional 2-D electrophoresis system.
The Ettan-DALT product is used for fingerprinting cellular proteins in research labs through a procedure referred to as "2-D electrophoresis." The unit provides a support and watertight enclosure for up to 6 glass-encased gels, each about 11 inches by 8 inches by 1.0-mm thick.
After incubation, the samples were mixed with Urea Mix for 2-D electrophoresis analysis, or with SDS Mix for 1-D analysis.
DNA microarrays, sequencing and 2-D electrophoresis imaging technologies are techniques that each bridge the research and diagnostic markets.
Sales of reagents for proteomics applications, in particular 2-D electrophoresis, were also strong.
The 2-D electrophoresis technology was gained from the acquisition of an ESA business just last month, and the MS system will be developed by HD Technologies and GSI.
Many biotech joint alliances have been aimed at combining technologies to produce integrated systems such as GSI and ESA's automated 2-D electrophoresis system.