two-dimensional gel electrophoresis

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two-dimensional gel electrophoresis

[¦tü·də‚men·shən·əl ¦jel i‚lek·trō·fə′rē·səs]
(cell and molecular biology)
A type of gel electrophoresis in which proteins are first separated by charge and then by molecular weight, enabling the analysis of complex protein mixtures.
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Interchangeable modular inserts enable users to combine vertical PAGE with capillary gel IEF to perform 2-D electrophoresis followed by Western transfer for enhanced sensitivity.
Products such as TotalLab and modas offer analysis and data mining tools for 1-D and 2-D electrophoresis gels and microarrays - the essence of genomics and proteomics.
I think that's where Bio-Rad can really make a difference because we're already strong in chromatography and sample preparation, and we're the market leader, for example, in 2-D electrophoresis," Dr.
Also, the joint research group has successfully reduced in size the new system to a quarter the conventional 2-D electrophoresis system.
After incubation, the samples were mixed with Urea Mix for 2-D electrophoresis analysis, or with SDS Mix for 1-D analysis.
Establishing a proteomics platform in the industrial setting initially requires implementation of a series of robotic systems to allow a high-throughput approach for analysis and identification of differences observed on 2-D electrophoresis gels.
Bio Image was previously focused on image analysis software for 2-D electrophoresis and high-density grids.
Ettan(TM) DIGE technology from Amersham Biosciences has significant benefits over classic 2-D electrophoresis, providing a very sensitive and accurate method for measuring differences in protein expression.
Many biotech joint alliances have been aimed at combining technologies to produce integrated systems such as GSI and ESA's automated 2-D electrophoresis system.
Newly updated 2-D electrophoresis gel image analysis software available from Amersham Biosciences, the life sciences company of Amersham (LSE:, NYSE:, OSE: AHM), is to help address critical bottlenecks of image analysis in proteomics research.