2-aminothiazole

2-aminothiazole

[¦tü ə‚mē·nō′thī·ə‚zȯl]
(organic chemistry)
C3H4N2S Pale-yellow crystals that melt at 92°C; soluble in cold water, slightly soluble in ethyl alcohol; used as an intermediate in the synthesis of sulfathiazole.
References in periodicals archive ?
Zou, "Chemical synthesis and characterization of conducting poly(2-Aminothiazole)," Materials Science Forum, vol.
The 2-aminothiazole scaffold has played an important role in medicinal chemistry and drug discovery research.
Determination of Hg in water by CVAAS using 2-aminothiazole modified silica.
[8] have found that Schiff bases derived from 2-aminothiazole exhibit antibacterial, antifungal and anti- inflammatory activities.
Here we are interested to study newly synthetized aminothiazoles, especially 2-aminothiazole derivatives which represent a class of heterocyclic ring system possessing antiviral [7], antimicrobial [8], anticancer [9], and anti-inflammatory activities [10].
In view of the importance of 2-aminothiazole and its derivatives, several methods were reported in the literature.
In these cases targeted compounds were obtained by cyclization of 2-aminothiazole derivatives with bis(methylthio)methylene malononitrile [15], benzylidene malononitrile [9], 2-acetylbutyrolactone [37], and formamide and formic acid [41].
Keywords: Multidrug resistance, Drug development, 2-Aminothiazole, Acylation of 2-aminothiazole, Antimicrobial activity.
Synthesis of 2-aminothiazoles and 2-thiazolecarboxamides with Anti-Anoxic Activity.
2-Aminothiazoles and their derivatives are well-known because of their wide spectrum of biological activity shown by the thiazole moiety [3-6].
2-Aminothiazoles and their derivatives have been used as pioneers for the synthesis of biologically active molecules [1-4].