hydroxylase

(redirected from 21-Hydroxylase)
Also found in: Dictionary, Medical, Wikipedia.

hydroxylase

[hī′dräk·sə‚lās]
(biochemistry)
Any of several enzymes that catalyze certain hydroxylation reactions involving atomic oxygen.
References in periodicals archive ?
Congenital adrenal hyperplasia (CAH) caused by deficiency of the 21-hydroxylase enzyme is the most common form of CAH worldwide.
The hormonal findings of the infant taken in dehydration-surrenal crisis treatment were in line with salt depleting 21-hydroxylase deficiency.
This is an autosomal-recessive genetic disorder with the vast majority (approximately 90%) caused by mutations in the CYP21A2 [6] (cytochrome P450 family 21 subfamily A member 2) gene (OMIM#613815), resulting in the loss of 21-hydroxylase activity (1).
The CYP21A2 gene coding for the 21-hydroxylase enzyme is formed by 10 exons and 9 introns located on the short arm of chromosome 6 [6,7].
In adrenals, Pcan be converted either into deoxycorticosterone under the control of 21-hydroxylase or 17-OHP by 17, 20 lyase.
1965) Spectrophotometric properties of a Tritonclarified steroid 21-hydroxylase system of adrenocortical microsomes.
Congenital adrenal hyperplasia (CAH) is caused by congenital insufficiency of the enzyme 21-hydroxylase (21-OHD) in the cortisol synthesis pathway.
It is a recessively inherited disorder and has an average incidence of 1:5000, the most common of these is 21-hydroxylase deficiency that accounts for 95% of involved cases1.
Classic congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is rare, occurring approximately once in every 15 000 live births.
There is a deficiency of an enzyme involved in the adrenal gland that causes a complete or partial deficiency of an enzyme involved in adrenal synthesis, the most common of which is 21-hydroxylase deficiency (CAH-21).
LISBON -- Women who receive long-term glucocorticoid treatment for congenital adrenal hyperplasia due to 21-hydroxylase deficiency are at risk for decreased bone mineral density, Jeremy A.