fluorouracil

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fluorouracil:

see metabolitemetabolite,
organic compound that is a starting material in, an intermediate in, or an end product of metabolism. Starting materials are substances, usually small and of simple structure, absorbed by the organism as food. These include the vitamins and essential amino acids.
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fluorouracil

[¦flu̇r·ō′yu̇r·ə‚sil]
(pharmacology)
C4H3FN2O2 Crystals that decompose at 282-283°C; used as an antineoplastic drug and as an inhibitor of deoxyribonucleic acid synthesis. Also known as 2,4-dioxo-5-fluoropyrimidine; 5-FU.
References in periodicals archive ?
Concurrent cisplatin 5-fluorouracil, leucovorin and radiotherapy for invasive bladder cancer.
Intralesional 5-fluorouracil, lidocaine and epinephrine mixture for the treatment of verrucae: a prospective placebo controlled, single-blind randomized study.
Hasegawa et al., "Prognostic significance of 5-fluorouracil metabolism-relating enzymes and enhanced chemosensitivity to 5-fluorouracil by 5-chloro 2,4-dihydroxypyridine in urothelial carcinoma," BMC Cancer, vol.
Pahlke et al., "5-Fluorouracil induces arterial vasocontractions," Annals of Oncology, vol.
Keywords: Pterygium, Recurrent pterygium, 5-fluorouracil. (JPMA 66: 559; 2016)
Intralesional 5-fluorouracil in the treatment of keloids: an open clinical and histopathologic study.
The two most commonly used regimes are cisplatin and 5-fluorouracil and cisplatin and bleomycin.
5-Fluorouracil (Eurofarma[R], Brazil) was obtained from the Laboratorio de Farmacologia da Inflamacao e do Cancer (LAFICA), Universidade Federal do Ceara (UFC) and used to induce intestinal mucositis.
Not only is 5-fluorouracil (5-FU) effective, "but it has become increasingly difficult to get some of the newer topical agents covered by health insurance plans, especially Medicare.
BERNALILLO, N.M.--Intravaginal 5-fluorouracil might be a better option than watchful waiting for women with stage II cervical intraepithelial neoplasia, according to a small trial from the University of North Carolina at Chapel Hill.
That list includes acne treatments formulated with doxycycline, minocycline, spironolactone, tetracycline, isotretinoin and tazorotone and the skin cancer treatment 5-fluorouracil.