5-Hydroxytryptophan

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5-hydroxytryptophan

[¦fīv hī¦dräk·sē′trip·tə‚fan]
(biochemistry)
C11H12N2O3 Minute rods or needlelike crystals; the biological precursor of serotonin.

5-Hydroxytryptophan

 

(also β-5-hydroxyindolyl-3-alanine), an amino acid. Two optically active forms and one racemic form exist for 5-hydroxytryptophan. In animals and man, L-5-hydroxytryptophan is produced as a result of the enzymatic hydroxylation of L-tryptophan during the conversion of L-tryp-tophan into the nervous-system mediator serotonin. When injected parenterally, 5-hydroxytryptophan has a hallucinogenic effect.

References in periodicals archive ?
Nonetheless, the amount of absorbed 5HTP could not change serotonin plasma levels.
After the 5HTP infusion, food intake was lower than after taking saline; however, tryptophan induced an increase in food intake.
Finally, complimenting the 5HTP ingredient and rounding out the essential Tone'd ingredients is Rhodiola Rosea.
The impurities in L-tryptophan were similar to the impurities found in 5HTP. Now the question remains: Are the impurities responsible for the rise in EMS, or is the metabolite 5HTP responsible?
The discovery that 5HTP can be extracted from a West African plant, Griffonia simplicifiola, means that a potent nutritional source of serotonin is now available.
It was reported that patients given 5HTP for depression had greater average improvement than patients given an anti-depressant drug.
You can't buy trytophan in this country, but you can get 5 Hydroxy Trytophan (5HTP), which is nearer to serotonin than trytophan.
Like 5HTP, tyrosine is available over the counter in this country.
Sorted Mango-flavoured effervescent tablets contain 5HTP, which converts to serotonin to lift low mood, plus ginseng to boost energy and electrolytes to rehydrate.
During this process, L-tryptophan is converted into 5-hydroxytryptophan (5HTP), which is the metabolic precursor of serotonin.
We report that 5HT and its immediate metabolic precursor, 5-hydroxytryptophan (5HTP), rapidly caused photopositive larvae of B.