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[¦āt hī¦dräk·sē′kwin·ə·lən]
(organic chemistry)
C9H6NOH White crystals or powder that darken on exposure to light, slightly soluble in water, soluble in benzene, melting at 73-75°C; used in preparing fungicides and in the separation of metals by acting as a precipitating agent. Also known as oxine; oxyquinoline; 8-quinolinol.



(also oxyquinoline, oxine); light yellow crystals with a melting point of 75°–76°C. 8-hydroxy-quinoline has the following structural formula:

Organic solvents, alkalis, and acids are good solvents for 8-hydroxyquinoline, but the compound is only slightly soluble in water. 8-hydroxyquinoline forms crystalline chelates, such as Mg(C9H6ON)2 and Al (C9H6ON)3; these are only slightly soluble in aqueous solutions, including acetic acid and ammonia. The capacity of 8-hydroxyquinoline to form chelates is used to detect and isolate a number of metals, including aluminum, zinc, cadmium, and magnesium. Some 8-hydroxyquinoline derivatives are used as fungicides, for example, the copper salt Cu(C9H6ON)2. Others, for example, Quinosol, Entero-Septol, and Yatren, are used as surface antiseptics or to kill amoebas.

References in periodicals archive ?
The halide substituents may be associated with the promiscuous behavior of iodochlorohydroxyquinoline in the [beta]-lactamase assays that is due to activity in the ARE-bla-mut assay, whereas the hydroxyl group in 8-hydroxyquinoline appears to be responsible for its activity in the ARE-bla and ARE-luc assays (and for the activity of iodochlorohydroxyquinoline in the ARE-luc assay).
1978, "In vivo and in vitro fates of 8-hydroxyquinoline derivatives in rat, " Chem.
3% of the total Al added was in a form that was kinetically reactive with 8-hydroxyquinoline in the 15-s reaction in the oak and pine extracts, respectively (Fig.
The organic fluorescent dyes in this work were coumarin 6, coumarin 7, pyrene, 2-methylanthracene, 9-methylanthracene, 9-bromoanthracene (9-BrAn), 9-phenylanthracene, 1-anthracenecarboxylic acid, Trinitrofluorene, 8-hydroxyquinoline aluminum (Alq3), and 1, 2-benzothiophene.
That is why, today, the role of the 8-hydroxyquinoline in Lantiseptic is to assure that there is no growth of microorganisms in the ointment.
Martinez, Electronic structure and reactivity analysis for a set of Zn-chelates with substituted 8-hydroxyquinoline ligands and their application in OLED, Org.
Patil and Shaikh [6] reported the synthesis, characterization and antibacterial studies of mixed ligand dioxouranium(VI) complexes prepared with 8-hydroxyquinoline as a primary ligand and amino acids.
Physiological role of 8-hydroxyquinoline sulphate and sucrose in the post harvest physiology of gladiolus cv.
Root tips were rinsed with deionized water, placed in 8-hydroxyquinoline for 2 h, and fixed in Carnoy's solution.
1% 8-hydroxyquinoline, 2% dimethyl sulfoxide (DMSO), and 10 mM tetrasodium EDTA, pH 13] was gently poured into the assembly to cover the slides to a height of approximately 6.
34 mol/L 8-hydroxyquinoline sulfate, one volume of 0.
The color developed by the reaction of ARG with 8-hydroxyquinoline in rumen fluid was stabilized by addition of excessive urea on ice instant.