retinoid

(redirected from 9-cis retinoic acid)
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retinoid

[′ret·ən‚ȯid]
(biochemistry)
The set of molecules composing vitamin A and its synthetic analogs, such as retinal or retinyl acetate.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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Alitretinoin (9-cis retinoic acid) is a naturally occurring retinoid that has anti-inflammatory and immunomodulatory effects.
To evaluate this method for lipidomic research and to further characterize the patterns of ABC transporters produced in cells relevant for atherosclerosis research, we monitored expression of mRNA in human primary monocytes, in vitro-differentiated macrophages, and cells stimulated with the liver-X-receptor (LXR) and retinoid-X-receptor (RXR) agonists T0901317 and 9-cis retinoic acid (RA) to mimic sterol loading and foam cell formation.
Cytochroma demonstrated that CYP26C, and not CYP26A or CYP26B, metabolizes 9-cis retinoic acid. All three members of the CYP26 family metabolize all-trans retinoic acid.