acetaminophen

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acetaminophen

(əsēt'əmĭn`əfĭn), an analgesicanalgesic
, any of a diverse group of drugs used to relieve pain. Analgesic drugs include the nonsteroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, acetaminophen, narcotic drugs such as morphine, and synthetic drugs with morphinelike action such as meperidine
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 and fever-reducing medicine. It is an active ingredient in many over-the-counter medicines, including Tylenol and Midol. Introduced in the early 1900s, acetaminophen is a coal tar derivative that acts by interfering with the synthesis of prostaglandinsprostaglandin
, any of a group of about a dozen compounds synthesized from fatty acids in mammals as well as in lower animals. Prostaglandins are highly potent substances that are not stored but are produced as needed by cell membranes in virtually every body tissue.
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 and other substances necessary for the transmission of pain impulses. Although its action is similar to that of aspirinaspirin,
acetyl derivative of salicylic acid (see salicylate) that is used to lower fever, relieve pain, reduce inflammation, and thin the blood. Common conditions treated with aspirin include headache, muscle and joint pain, and the inflammation caused by rheumatic fever and
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, it lacks aspirin's anti-inflammatory and blood-thinning effects, is less irritating to the stomach, and can be used by people who are allergic to aspirin. Heavy use, however, has been linked to an increased incidence of liver failure, especially in heavy drinkers of alcoholic beverages and in those who are not eating enough, and overdose, especially in children, can be fatal.

acetaminophen

[ə‚sēd·ə′mēn·ə·fən]
(organic chemistry)
C8H9O2N Large monoclinic prisms with a melting point of 169-170°C; soluble in organic solvents such as methanol and ethanol; used in the manufacture of azo dyes and photographic chemicals, and as an analgesic and antipyretic.
References in periodicals archive ?
With some coaching from ACETS staff, applicants submitted a cover letter, a resume, and two letters of reference.
They agreed to adhere to deadlines for completing their goals and to report their progress online to ACETS staff.
Participants remained in contact with ACETS via phone, email, real time computer interaction (chatting), and/or face-to-face contact.
As a particularly innovative feature, ACETS utilized a range of technology to provide "e-coaching", online support, coaching, and tracking.
ACETS also used this reporting mechanism as a means by which participants could document their difficulties and request needed supports.
Data presented on the outcomes of ACETS is based on all participants from year one of ACETS.
This instrument was given to the participants prior to their participation in ACETS and then again at the conclusion of the one-year of training and support provided by ACETS.
The first instrument, ACETS Employment Survey, was developed based on the ACES questionnaire (Bryen et al, 1995) and employment-related "hard" and "soft" skills identified from the general employment field especially related to information technology (e.