injury

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injury

Law a violation or infringement of another person's rights that causes him harm and is actionable at law
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005

injury

[′in·jə·rē]
(medicine)
A structural or functional stress or trauma that induces a pathologic process.
Damage resulting from the stress.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Given the above, it is concluded that the selection of the type of anesthetic during general anesthesia remains an important clinical issue, and that further research is needed to clarify the protective effect of inhalational anesthetics on the occurrence of AKI.
An interesting paper explores the future use of electronic health records (EHR) using algorithms to identify early those at risk, with the potential to either moderate or prevent AKI. This alert system, however, needs more evidence to support the development of sensitive decision-making algorithms with linkage to CPG (KDIGO).
On the other hand, pharmacotherapy used in cancer patients may also be responsible for prerenal AKI. Commonly used pain killer such as nonsteroidal anti-inflammatory drugs may contribute to acute kidney injury in patients by affecting renal hemodynamics, and reducing effective circulating volume.
Serum creatinine is the most widely employed marker of AKI. However, it is a late marker, highly nonspecific to the site or type of injury.
It is a small protein that is easily excreted by the kidneys, and appears in the urine within 2 hours of AKI. NGAL levels in patients with AKI have been associated with the severity of their prognosis and can be used as a biomarker for AKI.
Table 2 describes the clinical characteristics in patients with or without AKI. Of the 206 patients studied, 77 (37.4%) developed AKI and 72 patients (93.5%) of AKI group, had systolic dysfunction.
Mortality rate was 32% among patients with any degree of AKI. Upon multivariate analysis, male gender (OR 7.890, 95% CI 1.223-50.906, p = 0.03) and hyponatremia on admission (OR 4.732, 95% CI 1.223-18.307, p = 0.024) were independently related to AKI developed during hospital stay.
AC607 is a novel biologic therapy under development for the treatment of AKI. AC607 also possesses potential applications in other grievous illnesses.
In a 10-year retrospective study (1996-2006), carried out at Fundacion Valle del Lili (FVL) in Cali (7), 2.1% prevalence of AKI in the pICU was found, using serum creatinine above 1.5 mg/dl as definition of AKI. A second prospective study (2009-2010) in this pICU, applying the pRIFLE Scale (8), found increased incidence at 4.9%.
Even so, the softness prevailing in the other real estate categories is being fully utilised by AKI. "It's a very good time because other costs associated with creating a wider footprint are going down EoAC" staff accommodation expenses are down appreciably and this has a positive impact on HR costs," said Al Khayyat.
Some toolmaking, and all maintenance, modification and management of over 600 current tools, are conducted in-house at AKI. The company also works with specialist outside toolmakers who are able to provide particular expertise.