Concomitant methotrexate is often part of the therapeutic regimen for patients receiving aTNF agents, as it can reduce the development of anti-drug antibodies and increase the efficacy of aTNF therapy in the treatment of RA [36-38].
A recent meta-analysis demonstrated that patients with RA treated with aTNF agents had a significant increase in HDL-C in the first 2 to 6 weeks of therapy, after which HDL-C remained stable .
Additionally, results from the Corrona registry demonstrated that patients with RA who received aTNF agents had a reduced risk of CV events compared with patients who received csDMARDs; however, glucocorticoid use, which maybe a surrogate marker of increased inflammation, was associated with a dose-dependent increase in risk of CV events .
The rats were randomly separated into three groups of eight rats as follows: sham-operated (SP), ACLT + normal saline (NS) (ACLT + NS); and ACLT + ATNF.
The rats in the ACLT + ATNF and ACLT + NS groups underwent ACLT surgery, while the rats in the SP group underwent knee joint exposure only, followed by suturing.
After 1 week, the rats in the ACLT + ATNF group were given ATNF (adalimumab) treatment every 2 days by subcutaneous injection at a dosage of 20 [micro]g/kg.
This project involves a large number of international collaborators, namely Dr Takahiro Nagayama (Kyoto University, J), Prof Ken Wakamatsu (Gifu University, J), Dr Tom Jarrett (IPAC/Caltech, USA) and Dr Baerbel Koribalski (ATNF, Aus).
Pekeur with Profs Kraan-Korteweg and de Blok, as well as Dr Baerbel Koribalksi (ATNF, AU) completed her study of the HI-to-optical diameter relation based on well-resolved ATCA interferometry data obtained for the first 17 LVHIS (Local Volume HI Survey) galaxies.
will provide expertise in telemedicine, in the form of applications that provide instant medical advice remotely over the network.
`For the first time we've searched behind the Milky Way and found hundreds of new galaxies no-one has seen before,' ATNF astronomer, Dr Raymond Haynes, says.
The discovery came after ATNF astronomers designed a special radio wave `receiver', for the Parkes telescope.
De Blok is also part of the LVHIS team (the Local Volume HI Survey a Compact Array radio survey of nearby galaxies lead by Dr Baerbel Koribalski, ATNF