Ciechanover, Aaron

(redirected from Aaron Ciechanover)
Also found in: Wikipedia.

Ciechanover, Aaron,

1947–, Israeli biochemist, M.D. Hebrew Univ.–Hadassah Medical School, Jerusalem, 1974; D.Sc. Technion (Israel Institute of Technology), Haifa, 1982. He has been on the faculty at the Technion since 1986. Ciechanover received the 2004 Nobel Prize in Chemistry with Avram HershkoHershko, Avram,
1937–, Israeli biochemist, M.D. Hebrew Univ.–Hadassah Medical School, Jerusalem, 1965, Ph.D. 1969. Hershko has been a professor at the Rappaport Faculty of Medicine at the Technion (Israel Institute of Technology), Haifa, since 1972.
..... Click the link for more information.
 and Irwin RoseRose, Irwin,
1926–2015, American biochemist, b. Brooklyn, N.Y., Ph.D. Univ. of Chicago, 1952. Rose was on the faculty of Yale Medical School from 1954 to 1963 and a senior member of the Fox Chase Cancer Center in Philadelphia from 1963 until 1995.
..... Click the link for more information.
 for the discovery of the mechanism underlying protein degradation. Their work resulted in a molecular-level understanding of how cells control processes such as DNA repair, cell division, and immune functions by using a regulatory tag called ubiquitin to mark selected proteins for degradation. This knowledge has helped in the fight against diseases—for example, cystic fibrosis and cervical cancer—that result when the degradation is not carried out properly.
The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved.
References in periodicals archive ?
2004 Aaron Ciechanover, Avram Hershko and Irwin Rose "for the discovery of ubiquitin-mediated protein degradation"
BSF-sponsored U.S.-Israeli collaboration reached the pinnacle of scientific achievement in 2004, when the Nobel Prize for Chemistry was awarded to Professors Avram Hershko and Aaron Ciechanover of the Technion, and Professor Irwin Rose of the University of California, Irvine, for their joint discovery of the ubiquitin system of protein degradation, which regulates the breakdown of proteins governing almost all major functions of the cell.
The transaction is aimed at the development of a joint project, based on new findings by professor Aaron Ciechanover, Dr Gila Maor and professor Ofer Binah, that can potentially lead to the development of new anti-cancer drugs.
Yehoshua and David Grossman, Nobel Prize winning chemists Dan Shechtman and Aaron Ciechanover and the heads of major Israeli hospitals are also among those who signed the petition to Obama.
Among the numerous prizes Aaron Ciechanover received are the 2000 Albert Lasker Award, the 2003 Israel Prize, and the 2004 Nobel Prize (Chemistry; shared with Drs.
Proteologics is a biopharmaceutical company, which is in the business of discovery and research of drugs that are active on various components of the UBIQUITIN system, which was discovered by Drs Avram Hershko and Aaron Ciechanover - 2004 Nobel Prize in Chemistry laureates for the discovery of the UBIQUITIN system.
Five years ago my friend Professor Aaron Ciechanover together with his mentor Professor Avram Hershko, both of the Technion, won the Nobel Prize for chemistry for discovering the ubiquitin-mediated degradation system.
"The initial data presented by Rosetta is very significant" said Aaron Ciechanover, Nobel laureate and chairman of Rosetta's scientific advisory board.
Proceeds from the luncheon, attended by some 400 friends and supporters of ICRF, benefit ICRF's mission "to eliminate cancer for the benefit of the entire world by funding Israel's remarkable scientists." These scientists include the two Israelis who won the Nobel Prize in Chemistry in 2004, Professors Aaron Ciechanover and Avram Herskho.
Aaron Ciechanover and Avram Hershko of the Technion-Israel Institute of Technology in Haifa and Irwin Rose of the University of California, Irvine will share the prize, which was announced at press time.