"People know Abelcet
because of its applications, and people know Sigma-Tau because of its global footprint," offers Matthew VonEsch, Senior Director of Manufacturing at Sigma-Tau PharmaSource.
Intrapulmonary disposition of amphotericin B after aerosolized delivery of amphotericin B lipid complex (Abelcet
; ABLC) in lung transplant recipients.
(amphotericin B lipid complex) (product monograph) [electronic version].
Confusion over drug Amphotericin was created because the original "conventional" form, branded as Fungizone, has a dose of about 1mg per kg of a patient's weight, but modern forms, branded as Ambizone and Abelcet
, have dosages of 3mg and 5mg per kg.
Confusion over drug Amphotericin was created because the original "conventional" form, branded Fungizone, has a dose of one milligram per kg of patient's weight, but modern forms, Ambizone and Abelcet
, have doses of three and five milligrams per kg.
Known by the trade names Abelcet
, Ambisome, and Amphotec are lipid formulations of amphotericin B.
The drug comes under several names, including Fungizone, Abelcet
, AmBisome and Amphocil.
www.baxter.com TABLE: SIMILAR SOUNDING DRUG NAMES THAT COULD RESULT IN A MEDICATION ERROR Drug Name Confused With Abelcet
Amphotericin B Accupril Aciphex Acetazolamide Acetohexamide Aciphex Aricept Aciphex Accupril Activase TNKase Actonel Actos Adderall Inderal Advicor Altocor Aggrastat Argatroban Adapted from Medication Safety Alert.
Amphotericin B encapsulated in a liposome (Ambisome) or complexed with a lipid molecule (Abelcet
) may be more tolerable than amphotericin deoxycholate when given intravenously (Dupont, 2002).
Enzon plans to market Onco TCS through its entire North American sales force of approximately 60 people, which currently markets ABELCET
, ONCASPAR, and DEPOCYT to the oncology market.
INEX and Enzon are discussing the potential of transferring manufacturing to Enzon's sterile injectable manufacturing facility in Indianapolis, Indiana where Enzon manufactures its commercial drug ABELCET
(Amphotericin B Lipid Complex Injection) and where MYOCET (liposome encapsulated doxorubicin citrate complex) is manufactured for Elan Corporation, plc.
Last month Elan raised $370 million through the sale of US, Canadian and Japanese rights to its anti-fungal treatment Abelcet
and another $50 million with the sale of its cancer treatment Actiq.