New junior doctor, Dr Kiran Tawana, prescribed the generic name of Amphotericin for five milligrams after referring to a problematic internet version of a medicines manual that took her to a page for Abelcet
INEX and Enzon are discussing the potential of transferring manufacturing to Enzon's sterile injectable manufacturing facility in Indianapolis, Indiana where Enzon manufacturers its commercial drug ABELCET
(Amphotericin B Lipid Complex Injection) and where MYOCET (liposome encapsulated doxorubicin citrate complex) is manufactured for Elan Corporation, plc.
Last month Elan raised $370 million through the sale of US, Canadian and Japanese rights to its anti-fungal treatment Abelcet
and another $50 million with the sale of its cancer treatment Actiq.
The company has announced that it plans to find buyers for Azactam, Maxipime and Abelcet
, three drugs used by hospitals to fight infections.
Three different lipid preparations of amphotericin B are now commercially available: Abelcet
, AmBisome, and Amphotec.
Enzon's speciality pharmaceutical business includes the marketed products Oncaspar, Adagen, DepoCyt and Abelcet
, as well as a manufacturing facility in Indianapolis, Indiana.
Confusion over drug Amphotericin was created because the original "conventional" form, branded as Fungizone, has a dose of about 1mg per kg of a patient's weight, but modern forms, branded as Ambizone and Abelcet
, have dosages of 3mg and 5mg per kg.
Confusion arose as the original form of Amphotericln, branded as Funglzone and referred to as "conventional", has a dose of about one milligram per kg of a patient's weight, but modern forms, branded as Amblzone and Abelcet
, have dosages of three and five milligrams per kg.
At Elan's extraordinary general meeting this week, shareholders approved the sale of rights over the drug Abelcet
for EUR370 million, and company chairman Garo Armen forecast Elan would exceed its cash target.
is marketed in the United States and other countries for the treatment of severe systemic fungal infection.