Aspirin use also was associated with an increased risk of major bleeding events compared with no aspirin (23.1 per 10A-000 participant-years with aspirin and 16.4 per 10[euro]A-000 participant-years with no aspirin) (HR, 1.43 [95% credible interval, 1.30-1.56]; absolute risk increase
, 0.47% [95% CI, 0.34%-0.62%]; number needed to harm, 210).
found that prenatal exposure to N[O.sub.x] was associated with an absolute risk increase
of 3.8% for persistent asthma at age of 5, while exposure to N[O.sub.x] during the 1st year of life was associated with an absolute risk-increase of 4.0% for persistent asthma .
The increased risk of ectopic pregnancy (HR, 1.09) with overall primary C-sections translated to an absolute risk increase
of 0.1% and number needed to harm of 1,000 women.
suggested that exposure to fluoxetine and paroxetine in early pregnancy is associated with a small but established risk of specific cardiovascular anomalies; fluoxetine is associated with isolated ventricular septal defects (0.5% absolute risk increase
) and paroxetine is associated with right ventricular outflow tract defects (0.2% absolute risk increase
Although the relative risk increase was 33%, the absolute risk increase
was very small, at 0.27%," said Dr.
Therefore, compared with non-drinking women, women consuming 2 or more drinks per day had an absolute risk increase
of 0.66 events/1 000 person-years.