abzyme


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abzyme

[′ab‚zīm]
(immunology)
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Royersford, PA, August 03, 2017 --(PR.com)-- Abzyme Therapeutics LLC, a biotechnology company focused on developing antibodies for diagnostic and therapeutic applications, has filed a patent application entitled "Composition and Method for Diversifying Polypeptide Libraries," USPTO number 62/387,511.
As the founder-director of the Abzyme Research Foundation, Barnett is putting his energies into a vaccine.
To date, abzyme research largely has been limited to reactions that occur in aqueous solutions.
In addition to this wide array of functions, antibodies under certain conditions also exhibit an enzymatic or catalytic activity and are called "abzymes" (antibody enzymes).
[40.] Nevinsky GA, Kanythkova TG (2002) Natural catalytically active antibodies (abzymes) in health and diseases.
In the years since, catalytic antibodies, sometimes called abzymes, have attracted commercial, scientific, and medical interest.
Other proposed applications of mouse monoclonal antibodies include the use of antibodies with enzyme activity ("abzymes") as antiviral, anticancer, and thrombolytic therapeutic agents (75).
They call these catalytic antibodies "abzymes," and they hope to develop them as tools that will break peptide bonds, thus cleaving proteins with the same precision as the enzymes now used to cleave DNA.