acetamide

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acetamide

[ə′sed·ə‚mīd]
(organic chemistry)
CH3CONH2 The crystalline, colorless amide of acetic acid, used in organic synthesis and as a solvent.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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To overcome the limitations mentioned above of CPT-based treatment against NSCLC, we preliminarily examined a panel of acetamide derivatives and screened out a candidate N-[2-(morpholin-4-yl)phenyl]-2-{8-oxatricyclo[7.4.0.0, 2,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yloxy} acetamide (NPOA).
Accordingly, the acetamide derivative NPOA might be a promising sensitizer to CPT-based lung cancer therapy in the future and is worthy of further investigation.
As 1b, N-ethyl derivative 1d was converted slowly and the sole product identified was acetamide 3d (after 10 h 1d (71%), 3d (29%)) (Figure 5).
The single crystal of 2-(2,6-dichlorophenyl)-N-(1,3-thiazol-2-yl) acetamide is grown by slow evaporation method (melting point = 489491K) [22].
We have performed a test on the scaling of calculated vibrational bands in case of 2-(2,6-dichlorophenyl)-N(1,3-thiazol-2yl) acetamide, adopting two different scaling schemes, namely, scale factor and scaling equation.
Can-Eke, Synthesis and Evaluation of Antioxidant Properties of Novel 2- [2-(4-Chlorophenyl)benzimidazole-1-yl]-N-(2- arylmethyleneamino) acetamides and 2-[2-(4- Chlorophenyl)benzimidazole-1-yl]-N-(4-oxo-2- aryl-thiazolidine-3-yl) acetamides-I, Chem.
Saturnino, Acetamide Derivatives with Antioxidant Activity and Potential Anti-Inflammatory Activity, Molecules, 15, 2028 (2010).
Can-Eke, Synthesis and Evaluation of Antioxidant Properties of Novel 2- [2-(4-chlorophenyl) benzimidazole-1-yl]-N-(2- arylmethylene amino) acetamides and 2-[2-(4- chlorophenyl) benzimidazole-1-yl]-N-(4-oxo-2- aryl-thiazolidine-3-yl) acetamides-I, Chem.
In an effort to synthesize dipyrromethane derivatives that could act as anion recognizers with biological activity, we prepared a novel N-(2,2-di(1H-pyrrol-2-yl)ethyl)adamantane-1carboxamide 1 (Figure 4) as a structural analog of 2-amino-N-(adamant-2-yl) acetamide inhibitors of the 11[beta]-HSD.
A new series of N-alkyl/aryl substituted 5-(4-chlorophenyl)-1,3,4-Oxadiazol-2-yl-2-sulfanyl acetamide have been synthesized.
N-[(4-Substituted-phenyl)-2-substitutedthiocarbonylthio] acetamide Derivatives (4a-4s).
On the basis of above mentioned cumulative evidences, the structure of 3 was assigned as N-(4-(N- (5-chloro-2-methoxyphenyl)sulfamoyl)phenyl) acetamide. Similarly, the structures of other compounds were characterized by 1H-NMR, IR and mass spectral data as described in experimental section.