Acetic Anhydride

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Related to Acetic Anhydride: acetic acid

acetic anhydride

[ə′sēd·ik an′hīd‚rīd]
(organic chemistry)
(CH3CO)2O A liquid with a pungent odor that combines with water to form acetic acid; used as an acetylating agent.

Acetic Anhydride


(CH3CO)2O, a colorless liquid with a pungent odor. Acetic anhydride is soluble in benzene, ether, and other organic solvents; it has a boiling point of 139.5°C and a density of 1.082 g/cm3 at 20°C. Acetic anhydride is one of the reactants widely used in chemical synthesis for introducing the acetyl radical (CH3CO—), a process known as acetylation. Examples are provided by the reactions with alcohols (ROH) to form esters (CH3COOR), with amines (RNH2) to form amides (CH3CONHR), and with mercaptans (RSH) to form thioethers (CH3COSR). When heated with water, acetic anhydride forms acetic acid.

In industry, acetic anhydride is obtained by such methods as the catalytic oxidation of acetaldehyde in the presence of the acetates cobalt and copper and the reaction of acetic acid with ketene. The compound is mainly used in producing cellulose acetate, acetopropionate, and acetate butyrate; these substances in turn are used in making synthetic fibers, plastic products, coatings, paints, varnishes, and the backing of photographic and motion-picture film, as well as in producing such odoriferous substances as acetanisole and such pharmaceuticals as phenacetin.

References in periodicals archive ?
As illicit heroin production has grown, there has been a 35-fold increase in seizures of illegitimate shipments of acetic anhydride since 2012.
Amino acid samples were reacted with approximately a 10,000-fold molar excess of acetic anhydride for 10 min.
Acetylation with acetic anhydride is the only active chemical modification which has been scaled to a commercial process (Rowell 2006).
Cyclodehydration was accomplished by adding acetic anhydride and fused sodium acetate (22.
Ominously, Kazakhstan, a newly independent republic of former Soviet Central Asia, has recently become a major manufacturer of acetic anhydride, supplying the clandestine laboratories of nearby Afghanistan.
Global Acetic Anhydride Market 2015-2019 : The Global Acetic Anhydride market can be segmented on the basis of application into: Cellulose Acetate, Pharmaceuticals, TAED, PTMEG, and others.
A little bit later, police conducted an urgent search of the house of a relative of one of the detainees, when a sealed box was found in a house's room with 40 packages inside containing white powder with a specific smell of acetic anhydride, a total weight of which made 20 kg 800 grams.
204 Kgs Charas, 400 Gms Opium and 200 Kgs Acetic Anhydride, while arrested 16 persons and seized 5 vehicles.
The Government of Afghanistan informed the INCB that there is no legitimate use for acetic anhydride in Afghanistan and now seeks to block all imports of the substance.
It noted that while chemicals such as acetic anhydride, anthranilic acid, phenylacetone, and ephedrines help make a range of medicinal products; these substances can also help make narcotics and psychotropic drugs, which is why they are now controlled with anti-diversion laws in many developed countries.
During the past few years, many laboratories around the world have concentrated their efforts in the acetylation of biomass using liquid acetic anhydride.
05/kg in Latin America, Europe and Asia for acetic anhydride.