acetylcholine receptor

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acetylcholine receptor

[ə‚sed·əl ′kō‚lēn ri‚sep·tər]
(cell and molecular biology)
A receptor in the membranes of certain cell structures, such as synapses or the neuromuscular junction, to which the transmitter substance acetylcholine binds. Nicotinic acetylcholine receptors are gated ion channels that open in response to acetylcholine, leading to an increase in membrane conductance; muscarinic acetylcholine receptors are G-protein-linked receptors inducing membrane ion channel changes or intracellular processes such as smooth muscle contraction.
References in periodicals archive ?
Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies.
Muscarinic acetylcholine receptor subtypes in cerebral cortex and hippocampus.
Using the muscle nicotinic acetylcholine receptor antagonist hexamethonium, we found that the most effective method of drug administration for behavioral experiments was the immersion of sea urchins in drug solution for an hour, coupled with performing the behavioral experiments in the drug solution.
Levey, "Muscarinic acetylcholine receptor subtypes in cerebral cortex and hippocampus," Progress in Brain Research, vol.
Antagonist of M1 muscarinic acetylcholine receptor prevents neurotoxicity induced by amphetamine via nitric oxide pathway.
Misawa, "Critical roles of acetylcholine and the muscarinic and nicotinic acetylcholine receptors in the regulation of immune function," Life Sciences, vol.
The brain lesions of cholinergic nuclei or acetylcholine receptors (postsynaptic muscarinic [M.sub.1] receptors and presynaptic muscarinic [M.sub.2] receptors) and use of cholinergic antagonists are often related to cause cognitive dysfunctions similar to those observed in dementia [28-30].
Schneider, "[125I]Iodomethyllycaconitine binds to [alpha]7 nicotinic acetylcholine receptors in monkey brain," European Journal of Neuroscience, vol.
Acetylcholine Receptors. AChRs were visualized and quantified in all groups of mice (Figure 3).
It is caused by antibody mediated autoimmune attack against postsynaptic nicotinic acetylcholine receptors [1, 2].
Nonfunctioning acetylcholine receptors are resistant to depolarizing agents like succinylcholine and paralysis is prolonged when achieved with higher doses [12].
Anti- acetylcholine receptor antibodies titre was more than 60 nmol/L (Normal: less than .04nmol/L)