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acetyl derivative of salicylic acid (see salicylatesalicylate
, any of a group of analgesics, or painkilling drugs, that are derivatives of salicylic acid. The best known is acetylsalicylic acid, or aspirin. Now often made synthetically, they were originally derived from salicin,
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) that is used to lower fever, relieve pain, reduce inflammation, and thin the blood. Common conditions treated with aspirin include headache, muscle and joint pain, and the inflammation caused by rheumatic fever and arthritis. Aspirin is believed to act against fever, pain, and inflammation by interfering with the synthesis of specific prostaglandinsprostaglandin
, any of a group of about a dozen compounds synthesized from fatty acids in mammals as well as in lower animals. Prostaglandins are highly potent substances that are not stored but are produced as needed by cell membranes in virtually every body tissue.
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 in the body. Because of its ability to inhibit the formation of blood clots, aspirin is also used in low doses to prevent heart attack and stroke in persons with cardiovascular disease and to control unstable angina. The drug's usefulness in preventing certain cancers, the dangerous high blood pressure that sometimes occurs during pregnancy (toxemia), and migraine headaches is also under investigation.

Normal dosage may cause nausea, vomiting, diarrhea, or gastrointestinal bleeding. Large doses cause acid-base imbalance and respiratory disturbances and can be fatal, especially in children. Aspirin also has been linked to the development of Reye's syndrome (a combination of acute encephalopathy and fatty infiltration of internal organs) in children who have taken it for viral infections. Acetaminophenacetaminophen
, an analgesic and fever-reducing medicine. It is an active ingredient in many over-the-counter medicines, including Tylenol and Midol. Introduced in the early 1900s, acetaminophen is a coal tar derivative that acts by interfering with the synthesis of
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 (Tylenol), which does not cause gastric irritation but does lower fever and relieve pain, is often substituted for aspirin.

Aspirin, although usually made synthetically now, was originally derived from salicin, the active ingredient in willow bark. Willow bark had been used for centuries in folk medicine in certain parts of the world. Acetylsalicylic acid was first prepared by the German chemist Felix Hoffmann, an employee of Friedrich Bayer & Co., in 1897. It is now the active ingredient in many over-the-counter preparations; estimates put American consumption at 80 billion tablets annually.

See analgesicanalgesic
, any of a diverse group of drugs used to relieve pain. Analgesic drugs include the nonsteroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, acetaminophen, narcotic drugs such as morphine, and synthetic drugs with morphinelike action such as meperidine
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The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved.


(organic chemistry)
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.


1. a white crystalline compound widely used in the form of tablets to relieve pain and fever, to reduce inflammation, and to prevent strokes. Formula: CH3COOC6H4COOH
2. a tablet of aspirin
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005


(language, tool)
A freeware language from MITRE Corporation for the description of neural networks. A compiler, bpmake, is included. Aspirin is designed for use with the MIGRAINES interface.

Version: 6.0, as of 1995-03-08.
This article is provided by FOLDOC - Free Online Dictionary of Computing (
References in periodicals archive ?
Therefore, if there is a need for a NSAID in such cases, one could rather use: 1) acetylsalicylic acid or paracetamol (if analgesic or antipyretic effect is needed and there are no contraindications); 2) low-fixed dose or topic NSAIDs (theoretically less risky, but without studies corroborating that) (1,2,5,6,12,14,18).
Diabetic patients received more diuretic and acetylsalicylic acid but less calcium channel blocker.
Given the patient use of acetylsalicylic acid/dipyridamole for over five years, interstitial nephritis secondary to acetylsalicylic acid and dipyridamole was on the differential.
pylori infection and increased use of drugs that affect the cytoprotective function of gastric mucosa (NSAIDs and acetylsalicylic acid), which has also been shown in other studies (20).
In suspicion of allergic aetiology of unknown origin treatment with acetylsalicylic acid was terminated.
In the journal Laboratory Investigation, researchers at the Kansas City Veterans Affairs Medical Center report a protective effect for aspirin (acetylsalicylic acid) against the development of breast cancer in cell cultures and in mice that received tumor implants.* The findings also suggest a role for aspirin in preventing breast cancer relapse.
Objective: To Observe the histological and morphological effects of acetylsalicylic acid (ASA) on spermatogenesis in male albino mice.
There were primary open-angle glaucoma, diabetes mellitus, and usage of acetylsalicylic acid in patient's history.
Aspirin, or acetylsalicylic acid, was discovered by Edward Stone, an Oxford scientist, in 1763 as a derivative of the willow tree.
The company's most popular brands are Acetylsalicylic Acid, Ibalgin, Antinevralgic P and Paracetamol, together with Algocalmin, which switched to Rx in 2011.
: ABSTRACTObjective: Several studies have demonstrated the beneficial role of antiplatelet therapy with acetylsalicylic acid (ASA) at atherosclerotic vascular disease.
Drugs like acetylsalicylic acid are nowadays prescribed as a life style drug for the elderly.