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A condition of decreased alkali reserve of the blood and other body fluids.



a change in the acid-alkaline balance of the organism as a result of insufficient removal and oxidation of organic acids (for example, beta-hydroxybutyric acid). Usually these products are rapidly removed from the body. In febrile diseases, intestinal disorders, pregnancy, starvation, and such, they are retained in the body; this is manifested in mild cases by the appearance of acetoacetic acid and acetone in the urine (so-called ketonuria). In severe cases (for example, diabetes mellitus) it may lead to coma. Treatment consists of removal of the cause of acidosis (for example, by administering insulin in case of diabetes); there is also symptomatic treatment—soda and an abundance of fluids taken internally.

References in periodicals archive ?
The presence of metabolic acidaemia or low bicarbonate is of additional value to the Apgar score in predicting poor outcome, as the Apgar score is often not done in real time and can therefore be unreliable.
METHYLMALONIC acidaemia (MMA) is a disorder which means the body is unable to process certain proteins and fats properly.
In a study23 in which uterine artery blood flow (UtBF) and umbilical vein blood flow (UmBF) of IP and salbutamol in non-labouring chronic sheep preparations were investigated, it was reported that during the administration of IP and salbutamol to lambs, UtBF and maternal arterial pressure decreased significantly and that tachycardia, hyperglycaemia and acidaemia developed.
11] The presence of these biophysical variables implies absence of significant central nervous system hypoxaemia and acidaemia at the time of testing.
The NHS Newborn Blood Spot Screening programme will be expanded to screen for homocystinuria (HCU), maple syrup urine disease (MSUD), glutaric aciduria type 1 (GA1) and isovaleric acidaemia (IVA).
But the new scheme will check the same blood sample for five extra conditions: maple syrup urine disease, homocystinuria and three types of acidaemia.
The first step in assessment of the arterial blood gas profile is appraisal of the pH: a reduced pH indicates acidaemia and an elevated pH indicates alkalaemia (Table 1).
Four of these patients were changed to pressure support mode soon after the Vts were recorded, with subsequent improvement in acidaemia.
Umblical cord blood PH and risk factors for acidaemia in neonates in kerman.
Neurological dysfunction in methylmalonic acidaemia is probably related to the inhibitory effect of methylmalonate on brain energy production.
Courteney was born with propionic acidaemia, a rare disorder in which vital enzymes are missing.