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A condition of decreased alkali reserve of the blood and other body fluids.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a change in the acid-alkaline balance of the organism as a result of insufficient removal and oxidation of organic acids (for example, beta-hydroxybutyric acid). Usually these products are rapidly removed from the body. In febrile diseases, intestinal disorders, pregnancy, starvation, and such, they are retained in the body; this is manifested in mild cases by the appearance of acetoacetic acid and acetone in the urine (so-called ketonuria). In severe cases (for example, diabetes mellitus) it may lead to coma. Treatment consists of removal of the cause of acidosis (for example, by administering insulin in case of diabetes); there is also symptomatic treatment—soda and an abundance of fluids taken internally.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
The relationship between antenatal and intrapartum risk factors for fetal acidaemia was analysed using logistic regression model presented as odds ratio (OR) with 95% confidence intervals (CI).
Only 1.4% of infants with HIE 1 died, as opposed to 7.1% and 62.5% of those with HIE 2 and 3 respectively, defining asphyxia with inclusion of metabolic acidaemia. There were no deaths among those who did not develop HIE.
These cases represent over 60% of all IMDs diagnosed in this period and the majority fall into 3 main categories, namely the organic acidaemias (OAs), the urea cycle defects (UCDs) and the mitochondrial cytopathies.
Fetal heart rate patterns and ECG ST segment changes preceding metabolic acidaemia at birth.
Diagnosis of isovaleric acidaemia by tandem mass spectrometry: false positive result due to pivaloylcarnitine in a newborn screening programme.
Intrapartum fetal surveillance aims to improve fetal outcomes by identifying fetuses with hypoxic acidaemia and has the potential to promote fetal health and improve neonatal status at birth.
Jack Beattie, nine, from Catchgate, near Annfield Plain, County Durham, was diagnosed with methylmalonic acidaemia when he was only 11 weeks old.
As the victim suffers from impaired liver function resulting in acidaemia and hyperinsulinaemia hepatic gluconeogenesis and glycogenolysis occur.
She was two weeks old when she was diagnosed with propionic acidaemia, a condition in which vital enzymes, produced mainly in the liver, are missing.
The management and outcome of propionic and methylmalonic acidaemia. J Inherit Metab Dis.