Acidophilia


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acidophilia

[ə‚sid·ə′fil·ē·ə]
(medicine)

Acidophilia

 

the capacity of cell structures to be stained by acid: eosin, acid fuchsine, picric acid, and others. Such structures are called oxyphile, eosinophilic, fuchsinophil, and so on. The cause of acidophilia is principally the basic (alkaline) properties of the stainable materials. Acidophilia is used to distinguish various cell structures, for example, in analyzing blood cells.

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Important liver architectural alterations (hepatic cell plates derangement, intense vacuolation, inflammatory influx, cytoplasmic acidophilia, and decharacterization of the nucleus of hepatocytes) were observed in mice treated with UA (2000 mg/kg; p.o.), whereas at the same dose UA-micro-treated animals showed plates of hepatic cells and sinusoids but preserved hepatocytes nuclei.
The zona radiata was wider than in the middle phase, and exhibited a strong acidophilia (Fig.
The eggs observed in the initial phase are characterised by intense acidophilia. They are identified by their spherical and regular structure, covered by an acellular envelope appearing slightly basophilic.
Several bundles of muscle (M) just above the exocuticle are evident from their strong acidophilia after staining with hematoxylin and eosin.