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A condition of decreased alkali reserve of the blood and other body fluids.



a change in the acid-alkaline balance of the organism as a result of insufficient removal and oxidation of organic acids (for example, beta-hydroxybutyric acid). Usually these products are rapidly removed from the body. In febrile diseases, intestinal disorders, pregnancy, starvation, and such, they are retained in the body; this is manifested in mild cases by the appearance of acetoacetic acid and acetone in the urine (so-called ketonuria). In severe cases (for example, diabetes mellitus) it may lead to coma. Treatment consists of removal of the cause of acidosis (for example, by administering insulin in case of diabetes); there is also symptomatic treatment—soda and an abundance of fluids taken internally.

References in periodicals archive ?
2] with the accompanying respiratory acidosis will cause a decrease in plasma lactate concentration (LA) during and after a bout of exercise.
The concern is for development of lactic acidosis in patients because the renally excreted metformin may build up as a result of decreased renal function.
Linear regression analyses identified a significant correlation of plasma D-lactate concentration with acidosis (bicarbonate, r = -0.
Alterations in plasma pH may also be due to metabolic acidosis or alkalosis.
Of the 35 patients with elevated lactate levels, 43% (n=15) were obese and 4 (11%) died due to complications of lactic acidosis.
The management of hypercapnia may depend on whether it is acute or acute on chronic with hypercapnic acidosis or chronic with metabolic compensation.
Alkali supplementation therapy such as bicarbonate is used to treat CKD patients with severe metabolic acidosis, but simply adding more fruits and vegetables-which contain alkali-to the diet might also help.
We would like to emphasize that bicarbonate treatment is not efficient and early hemodialysis or hemodiafiltration are life-saving in patients who develop severe acidosis (pH < 7.
Karl has a metabolic and respiratory acidosis with hypoxemia.
Acidosis can lead to reduced milk production and butterfat, in addition to lameness, poor fertility and general health problems.