An exceedingly peculiar variant of this tumor has been described as acinic cell carcinoma
with high-grade transformation/dedifferentiation which is characterized by the coexistence of both low-grade acinic cell carcinoma
and a high-grade dedifferentiated component, as well as by an accelerated clinical course.
Tumors for which this phenomenon is well characterized include acinic cell carcinoma
, adenoid cystic carcinoma, and epithelial-myoepithelial carcinoma.
 Acinic cell carcinoma
was diagnosed in 4 (3.50%) cases, 2 cases each were seen in parotid and submandibular glands and was seen in 3rd and 5th decade which is similar to the study conducted by Fernandes GC et al.15 Two case of adenoid cystic carcinoma were diagnosed involving the minor salivary glands which are also similar to other studies .
Parotid acinic cell carcinoma
is a rare, slow-growing, malignant tumor with imaging findings indistinguishable from other parotid tumors.
Acinic cell carcinoma
may be distinguished by DOG1 positivity.
* Acinic cell carcinoma
of the jaw is extremely rare and, to our knowledge, only 8 cases have been reported in English literature.
Infiltration into the salivary gland parenchyma in the form of trabeculae, sheets, and nests (5) Pleomorphic adenoma Encapsulated, presence of chondromyxoid areas, characteristic melting pattern seen (6) Warthin's tumour Papillary cystic lesion with bilayered oncocytic epithelium overlying lymphoid stroma (7) Acinic cell carcinoma
Forms a solitary mass or multiple nodules and invades in broad fronts.
The most common types of parotid cancer (n = 672) were mucoepidermoid carcinoma (n = 270 [40.2%]), acinic cell carcinoma
(n = 200 [29.8%]), and adenoid cystic carcinoma (n = 61 [9.1%]).
Sinonasal acinic cell carcinoma
: a clinicopathologic study of four cases.
Multiple expression of tissue markers in mucoepidermoid carcinomas and acinic cell carcinomas
of the salivary glands.
National Cancer Data Base report on cancer of the head and neck: Acinic cell carcinoma
. Head Neck 1999;21 (4):297-309.
The tumors with frequent and high SOX10 expression are acinic cell carcinoma
, adenoid cystic carcinoma, epithelial-myoepithelial carcinoma, myoepithelial carcinoma, and pleomorphic adenoma, which presumably show similarities to acini and intercalated ducts.