aconitic acid

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aconitic acid

[‚ak·ə′nid·ik ′as·əd]
(organic chemistry)
C6H6O6 A white, crystalline organic acid found in sugarcane and sugarbeet; obtained during manufacture of sugar.
References in periodicals archive ?
SXSM-enhanced TCA cycle due to increased aconitate hydratase, succinyl-CoA ligase (GDP-forming) subunit alpha and beta (SUCLG1/2) and succinyl-CoA ligase (ADP-forming) subunit beta (SUCLGA2), isocitrate dehydrogenase2, and dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (DLAT, PDHB).
Full=Cytoplasmic aconitate hydratase; Short=Aconitase; AltName: Full=Citrate hydro-lyase; AltName: Full=Ferritin repressor protein; AltName: Full=Iron regulatory protein 1; Short=IRP1; AltName: Full=Iron-responsive element-binding protein 1; Short=IRE-BP UniProtKB/Swiss-Prot: Q01059.
Its toxicity is caused by sodium monofluoroacetate (MFA), which inhibits aconitate hydratase, one of the tricarboxylic acid cycle enzyme (LEE et al.
Three (30%) patients were suspected to have mitochondriopathy based on biochemical parametres which included elevated lactate in urine or plasma, elevated alanine in plasma amino acids, urine GC-MS showing elevation of one or more of the following compounds; Pyruvate, Succinate, Fumarate, Citrate and Aconitate (a metabolite in Kreb's cycle).
Due to the lack of Krebs cycle in mitochondria, the detection of aconitase and isocitrate dehydrogenase might suggest the existence of [alpha]-ketoglutarate as a metabolite of aconitate and isocitrate.
The root tips of ES8 and ET8 had similar organic anion profiles, with no significant differences in exudation of citrate, malate, aconitate, succinate, formate, or acetate between the ES8 and ET8line.
radioresistens 0 90 0 0 0 Trans- Phenyl Amino- Species Malonate aconitate * alanine * butyrate * A.
11 HCL-KCL buffer HCL-Glycine buffer HCL-Phthalate buffer Aconitate buffer Citrate buffer Acetate buffer Citrate-phosphate buffer Succinate buffer Phthalate-NaOH buffer Maleate buffer Cacodylate buffer Phosphate buffer Tris(hydroxymethyl)aminomethane -maleate buffer Barbital buffer Tris buffer Boric acid-borax buffer Propanediol buffer Glycine buffer Borax-NaOH buffer Carbonate-bicarbonate buffer pH 1.
Enzyme System AAT Aspartate aminotransferase ACO Aconitate hydratase ALD Fructose-bisphosphate aldolase AP-1 Glycil-leucine peptidase ARK Arginine kinase DIA Dihydrolipoamide dehydrogenase EST Esterase [beta]-GAL [beta]-galactosidase GAPDH Glyceraldehide-3-phosphate dehydrogenase GPI Glucose-6-phosphate isomerase G3PDH Glycerol-3-phosphate dehydrogenase NAD (+) IDH Isocitrate dehydrogenase NADP (+) LAP-1 Leucine aminopeptidase-1 LAP-2 Leucine aminopeptidase-2 MDH Malate dehydrogenase ME Malate dehydrogenase NADP (+) MPI Mannose-6-phosphate isomerase ODH D-octopine dehydrogenase PGD 6-phosphogluconate dehydrogenase PGM Phosphoglucomutase PP Phenyl-proline peptidase SOD Superoxide dismutase Abbr.
We analyzed seven different enzyme systems: aconitate hydratase (Acn), diaphorase (Dia), isocitrate dehydrogenase (Idh), malate dehydrogenase (Mdh), phosphoglucoisomerase (Pgi), phosphoglucomutase, (Pgm) and Triose-phosphate isomerase (Tpi).
Basal metabolism Aconitate hydratase Lipase Fructose-1,6-biphosphatase F-II Fructose-bisphosphate aldolase Alpha-amylase B 3-oxoacyl-ACP reductase C-4 sterol methyl oxidase 2 Amine oxidase Scavenger receptor cysteine-rich protein Vacuolar H+-ATPase C chain 4.