Most of commercialized glucose isomerases used in industrial scale are produced from Streptomyces spp., Arthrobacter spp., Actinoplanes
missouriensis, and Bacillus coagulans.
(2009) found that three rhizoactinomycetes Streptomyces MM40, Actinoplanes
ME3 and Micromonospora MM18 produced and released IAA, GA3, and zeatine in a defined media.
It is a glycopeptide antibiotic extracted from Actinoplanes
teichomyceticus with a similar spectrum of activity to vancomycin.
The dominant species belonging to 8 genera: Strptomyces spp., Pseudonocardia spp., Micromonospora spp., Actinoplanes
spp., Kribbella spp., Rhodococcus spp., Nocardia spp.
Acarbose, a complex of oligosaccharides isolated from Actinoplanes
sp., was discovered by Bayer pharmaceuticals for a search of [alpha]-glucosidase inhibitors (Shu, 1998).
Compound 4 was isolated from gram-negative bacteria Ralstonia metallidurans  and compound 10 was isolated from actinomycetes Actinoplanes
Phylogenetic analysis of the genus Actinoplanes
and transfer of Actinoplanes
minutisporangius Ruan et al.
The alpha glucosidase inhibitors (AGIs) were initially isolated from bacterial cultures or their derivatives: acarbose from Actinoplanes
, miglitol, a semisynthetic derivative of 1-deoxynojirimycin, from Bacillus and Streptomyces sp.,and voglibose, from validamycin A, a product of Streptomyces hygroscopicus var.
Some genera of this group are Actinomadura, Actinoalloteichus, Actinoplanes
, Amycolatopsis, Actinokineospora, Acrocarpospora, Actinosynnema, Catenuloplanes, Cryptospo -rangium, Dactylosporangium, Kibdelosporangium, Kineosporia, Kutzneria, Microbispora, Microtetraspora, Nocardia, Nonomuraea, Planomonospora, Planobispora, Pseudonocardia, Saccharomonospora, Saccharopolyspora, Saccharothrix, Salinispora, Streptosporangium, Spirilliplanes, Thermomonospora, Thermobifida, and Virgosporangium .
Initially patented in 1995 as Actinoplanes
sp or the bacteria strain called SE 50, the global marketing of the drug as Acarbose, commenced in 2000.
Su composicion, en terminos de los microorganismos que participan en la segunda fermentacion, esta mayoritariamente representada por Aspergillus niger pero con la presencia de otros hongos como el Blastobotrys adeninivorans (Abe et al, 2008), Actinoplanes
purpeobrunneus, Streptomyces bacillaris, Streptomyces cavourensis subsp.