actin

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actin,

a protein abundantly present in many cells, especially muscle cells, that significantly contributes to the cell's structure and motility. Actin can very quickly assemble into long polymer rods called microfilaments. These microfilaments have a variety of roles—they form part of the cell's cytoskeleton, they interact with myosinmyosin
, one of the two major protein constituents responsible for contraction of muscle. In muscle cells myosin is arranged in long filaments called thick filaments that lie parallel to the microfilaments of actin.
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 to permit movement of the cell, and they pinch the cell into two during cell division. In muscle contraction, filaments of actin and myosin alternately unlink and chemically link in a sliding action. The energy for this reaction is supplied by adenosine triphosphateadenosine triphosphate
(ATP) , organic compound composed of adenine, the sugar ribose, and three phosphate groups. ATP serves as the major energy source within the cell to drive a number of biological processes such as photosynthesis, muscle contraction, and the synthesis of
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.

actin

[′ak·tən]
(biochemistry)
A muscle protein that is the chief constituent of the Z-band myofilaments of each sarcomere.
References in periodicals archive ?
This partial actin gene fragment was sequenced by the dideoxynucleotide method from Centre for Applied Molecular Biology (CAMB), Lahore, Pakistan.
Ligation of actin was confirmed through restriction digestion.
BLAST (Basic Local Alignment Search Tool) has shown that this partial actin gene has 92% gene sequence similarity with Aspergillus terreus NIH2624 actin (ATEG_06973) partial mRNA and A.
Furthermore, the comparisons of actin genes from different fungi are very useful for phylogenetic studies.
Lane 1, 2, 3 Gel purified actin partial gene (760 bp), Lane 3: Marker (1 kb DNA ladder, Fermentas)
Isolation and characterization of actin gene from Tetrahymena thermophila.
The single-copy actin gene of Phytophthora megasperma encodes a protein considerably diverged from any other known actin.
Unusual nucleotide sequence at the 5 end of actin genes in Dictyostelium discoideum.
Actin-free Gc-globulin bound to the coat of a monoclonal antibody that is capable of binding Gc-globulin, free or complexed with actin, is detected with a second labeled monoclonal antibody that specifically binds to epitopes of the actin-free Gc-globulin.
The extracellular actin-scavenger system and actin toxicity.
The extracellular actin scavenger system in trauma and major surgery.