interstitial nephritis

(redirected from Acute interstitial nephritis)
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interstitial nephritis

[¦in·tər¦stish·əl nə′frīd·əs]
(medicine)
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Studies dating back 25 years, however, demonstrate that proton pump inhibitors themselves can induce acute interstitial nephritis, which is a condition in which spaces between the kidney tubules become swollen and interfere with filtration of toxins out of one's blood.
Various studies in different populations have demonstrated crescentric glomerulonephritis, IgA nephropathy, acute interstitial nephritis, focal segmental glomerulosclerosis, (27) membranous glomerulonephritis, and proliferative glomerulonephritis as the most frequent causes of NDRD.
The drugs that induce acute interstitial nephritis are given in Table 10.
Renal biopsy in eight patients demonstrated acute tubular injury in six cases, and features of acute interstitial nephritis in three.
The most common forms of intrinsic kidney injury are acute tubular necrosis (ATN), acute interstitial nephritis (AIN), and contrast-induced nephropathy (CIN).
In athletes NSAIDs may harm the kidneys by directly causing acute interstitial nephritis and indirectly by decreasing intra-renal blood flow.
Although the most commonly noted renal pathologic finding is acute interstitial nephritis, acute tubular cell necrosis is also described.

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