acute-phase protein

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acute-phase protein

[ə¦kyüt ¦fāz ′prō‚tēn]
(immunology)
Any of a group of proteins that are produced by the liver and appear in the blood in increased amounts shortly after the onset of infection or tissue damage; they include C-reactive protein, fibrinogen, proteolytic enzyme inhibitors, and transferrin.
References in periodicals archive ?
a1-Acid glycoprotein: an acute phase protein with inflammatory and immunomodulating properties.
As a well-known acute phase protein in cardiovascular diseases, hsCRP has been confirmed to be a diagnostic factor for CAD and to be associated with coronary angiographic severity.
Acute phase proteins are present in the blood and increase in concentration when inflammation occurs.
In particular CRP is a useful marker for infection in elderly patients and is superior both to other acute phase proteins and to the erythrocyte sedimentation rate [5-7].
Laparoscopic surgery causes less tissue injury than conventional procedures, so the increase in concentrations of biochemical markers of inflammation, such as IL-6 and the acute phase proteins CRP is not as high, while drop in albumin levels are also not so low.
Baltz, "Acute phase proteins with special reference to C-reactive protein and related proteins (pentaxins) and serum amyloid A protein," Advances in Immunology, vol.
Caption: Figure 2: Prohepcidin and acute phase protein levels during anti-TNF therapy.
CRP is an acute phase protein that is produced predominantly by the hepatocytes under the influence of cytokines such as Interleukin-6 and tumor necrosis factor-alpha.
Evaluation of a commercially available apparatus for measuring the acute phase protein serum amyloid A in horses.
Expression of Lcn2 in adipose tissue can be induced by lipopolysaccharides, suggesting Lcn2 to be an acute phase protein [5].
(14) In addition, they trigger the hepatic "acute phase response" resulting in increased synthesis and secretion of several acute phase proteins, including Cob binding protein (C4bBP).
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