acid chloride

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acid chloride

[′as·əd ′klȯr‚īd]
(organic chemistry)
A compound containing the radical ‒COCl; an example is benzoyl chloride.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The mixture was then transferred into a three necked flask at 70[degrees]C for 24 h to complete the acyl chloride functionalization.
Second, the grafting process is carried out via an amidation reaction occurred between the amine and acyl chloride groups formed on GO and carbon fibers, respectively.
Eventually, intermediate 4 reacted with a series of acyl chloride to give the target compounds 5a-o based on the published procedure [21].
Reagents and conditions: (a) thiourea, ethanol, and reflux; (b) chloroacetyl chloride, C[H.sub.2][Cl.sub.2], Et3N, r.t.; (c) morpholine, ethanol, [K.sub.2]C[O.sub.3], r.t.; (d) Sn[Cl.sub.2]-2[H.sub.2]O, ethanol, reflux; (e) substituted acyl chloride, C[H.sub.2][Cl.sub.2], [Et.sub.3]N, r.t.;
After 3h, the resulting solution was concentrated with a stream of dry nitrogen, redissolved in C[H.sub.2][Cl.sub.2], and brought to dryness once more with nitrogen to yield the acyl chloride as an oily solid.
Cinnamic acid dissolved in refluxing thionyl chloride with catalytic DMF was the preferred route for the synthesis of acyl chlorides destined for the synthesis of the ester, while the acyl chloride synthesized from cold oxalyl chloride in C[H.sub.2][Cl.sub.2] yielded much cleaner crude reaction mixtures and higher yields in the synthesis of the cinnamyl amide.
Patent 7,135,536 (November 14, 2006), "Production Method of Polyisocyanate by End-Capping With Acyl Chloride," Jae-Suk Lee, Chan Hee Jung, Sang-Yoon Park, Guttikonda Yogendra Nath, and Shashahar Samal (Gwangju Institute of Science and Technology, Gwangju, South Korea).
Polyisocyanates can be stabilized by capping a living polymer chain amidate anion with an acyl chloride in the presence of an amine catalyst.
As pointed out above, the amines were derivatized using (R)-MTP chloride as a HCDA, but as a result of the sequence rules, the configurational designation of the chiral center in the acyl MTP moiety changed from R- in the acyl chloride to S- in the amide derivatives.
After the addition, the system was kept stirring at 60[degrees]C for 24 more hours to allow the esterification between the acyl chloride groups on PACl and the hydroxyl groups on HEA to occur.
The formation of these moieties is also reported through the formation of acyl chlorides through oxalyl chlorides and thionyl chloride and then reaction of corresponding acyl chlorides with amine.[15, 16] The use of oxalyl chloride or thionyl chloride results in the formation of carbon monoxide so chemical and safety measures should be maintained.
The acyl and benzyl analogs of coniferyl alcohol were prepared by its reaction with acyl chlorides and benzyl chloride in acetone in presence of K2CO3 under reflux overnight [7].