adamantane

(redirected from Adamantyl)

adamantane

[‚ad·ə′man‚tān]
(organic chemistry)
A C10H16 alicyclic hydrocarbon whose structure has the same arrangement of carbon atoms as does the basic unit of the diamond lattice.
References in periodicals archive ?
Antibacterial activity of adamantyl substituted cyclohexane diamine derivatives against methicillin resistant Staphylococcus aureus and Mycobacterium tuberculosis.
Decomposition dose not simply progress in Block(61/39) and Block(36/64) because the thermal energy by heating was changed not only by decomposition of the adamantane unit but also the kinetic energy of polymer main chain, as the mobility of methacrylate main chain is derived more from the lower molecular weight of adamantyl methacrylate.
Santaniello, New Synthesis of 6[3-(1- adamantyl)-4-methoxyphenyl]-2-naphthoic acid and Evaluation of the Influence of Adamantyl Group on the DNA Binding of a Naphthoic Retinoid.
Surprisingly, introduction of the significantly larger adamantyl (12d) and triisopropylsilyl groups (12e) did not lead to loss of activity, while elimination of the three methyl groups from 1 diminished the potency 440-fold (12a).
In fact, the adamantyl group, when grafted to polymers, was shown to increase the glass transition temperature and the thermal stability of polymers [20, 21].
ALP activity was measured by the addition of 200 [micro]L of a chemiluminescent substrate, a phosphate ester of adamantyl dioxetane from the IMMULITE 2500 [TT.
Therefore the incorporation of the adamantyl moiety is capable to induce relatively high lipophilicity which can improve the biological availability of some molecules.
Sustained light emission is detected after injection of a phosphate ester of adamantyl dioxetane (chemiluminescent substrate) and is proportional to serum LBP concentrations.
The chemiluminescent substrate used for the enzymatic reaction is an ester of adamantyl dioxetane phosphate.
Finally, the chemiluminescent substrate, a phosphate ester of adamantyl dioxetane, is added.
Chemiluminescence enzyme immunoassay of alpha-fetoprotein based on an adamantyl dioxetane phenyl phosphate substrate.
Further studies on the application of chemiluminescent reactions and stabilized adamantyl dioxetane substrates for alkaline phosphatase labels in immunoassay and DNA analysis were undertaken in collaboration with Dr.