Dependovirus

(redirected from Adeno-associated virus)
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Dependovirus

[di′pen·də‚vī·rəs]
(virology)
A genus of the animal-virus family Parvoviridae that is characterized by defective viruses that require a helper virus (usually an adenovirus) for their replication.
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He and his associates have focused on the relatively nonpathogenic adeno-associated virus.
Protective effect of recombinant adeno-associated virus 2/8-mediated gene therapy from the maternal hyperphenylalaninemia in offsprings of a mouse model of phenylketonuria.
There is a major difference between adeno-associated virus vectors and adenovirus vectors,' he says.
A member of this family, the avian adeno-associated virus (AAAV) has been fully characterized [3, 8] and successfully used for gene delivery in chicken embryo tissues and cells [7, 8].
In a phase II trial, researchers used an adeno-associated virus to deliver the cystic fibrosis transmembrane conductance regulator gene to the lung epithelium.
Phase I trial results using an adeno-associated virus that is injected into muscle to provide factor IX offer hope for patients with this disease.
His experiments involved the use of adeno-associated virus vectors to transfer therapeutic genes to newborn mice.
The gene is contained in an adeno-associated virus (AAV) vector injected under ultrasound guidance into the quadriceps muscle.
AGTC's potential treatment uses an adeno-associated virus (AAV), a safe, man-made virus that delivers healthy copies of the ACHM gene to the cells of the retina, replacing the defective copies of the gene.
A002, an adeno-associated virus investigational gene therapy designed to deliver a codon-optimized CNGB3 cDNA under the control of the cone arrestin promoter to photoreceptors in the back of the eye, is delivered via a sub-retinal injection to cover the central region of the retina, including the fovea where the majority of cones are located.
The project will look at the manufacturing process for the adeno-associated virus.